Compile Data Set for Download or QSAR
Found 169 with Last Name = 'swinnen' and Initial = 'd'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50131550((3S)-3-{[(1S)-1-carbamoyl-2-{4-[difluoro(phosphono...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BGCPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50151008((7S)-2-[(carboxycarbonyl)amino]-7-({[(5-fluoro-1H-...)copy SMILEScopy InChI
Affinity DataKi:  18nMpH: 5.5Assay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B at pH 5.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BGCPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM15819(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)copy SMILEScopy InChI
Affinity DataKi:  77nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50108877((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450448(CHEMBL4176008)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50108877((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450452(CHEMBL4167128)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450450(CHEMBL4172614)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450447(CHEMBL4171117)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450452(CHEMBL4167128)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450454(CHEMBL4174978)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450473(CHEMBL4170443)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450450(CHEMBL4172614)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450447(CHEMBL4171117)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450465(CHEMBL4177089)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450468(CHEMBL4169861)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529561(CHEMBL4462175)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450462(CHEMBL4160303)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529577(CHEMBL4470211)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450467(CHEMBL4163421)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529578(CHEMBL4461693)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529585(CHEMBL4458006)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529576(CHEMBL4531460)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450448(CHEMBL4176008)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450453(CHEMBL4174102)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450453(CHEMBL4174102)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450449(CHEMBL4174117)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529575(CHEMBL4449462)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529574(CHEMBL4447751)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529572(CHEMBL4583818)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529571(CHEMBL4453736)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529573(CHEMBL4523002)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529570(CHEMBL4476127)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450469(CHEMBL4162990)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529580(CHEMBL4556206)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450470(CHEMBL4166574)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529560(CHEMBL4577912)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450464(CHEMBL4176890)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529562(CHEMBL4587566)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450444(CHEMBL4174751)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529565(CHEMBL4438313)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529569(CHEMBL4538981)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450455(CHEMBL4175239)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450463(CHEMBL4164621)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529584(CHEMBL4518323)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529581(CHEMBL4442598)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450453(CHEMBL4174102)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450465(CHEMBL4177089)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50450468(CHEMBL4169861)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300H8PubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandPNGBDBM50529582(CHEMBL4551380)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8047PubMed
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