Compile Data Set for Download or QSAR
Found 24 with Last Name = 'peeters' and Initial = 'dc'
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121279(2-Amino-1-[2-(5-ethyl-1H-imidazol-2-yl)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121284(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121282((S)-1-((S)-2-aminobutanoyl)-N-butylindoline-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121280(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121283(2-Amino-1-[2-(1H-imidazol-2-yl)-2,3-dihydro-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
LigandPNGBDBM50177043(CHEMBL3814671)copy SMILEScopy InChI
Affinity DataIC50: 339nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177042(CHEMBL3730906)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Research& Development

Curated by ChEMBL
LigandPNGBDBM50177033(CHEMBL3813839)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177041(CHEMBL3814491)copy SMILEScopy InChI
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50429613(CHEMBL2334590)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177040(CHEMBL3814642)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177039(CHEMBL3814308)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Research& Development

Curated by ChEMBL
LigandPNGBDBM50177032(CHEMBL3814407)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177038(CHEMBL3814655)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Research& Development

Curated by ChEMBL
LigandPNGBDBM50177031(CHEMBL3814969)copy SMILEScopy InChI
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Research& Development

Curated by ChEMBL
LigandPNGBDBM50177044(CHEMBL3814695)copy SMILEScopy InChI
Affinity DataIC50: 6.17E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177037(CHEMBL3814438)copy SMILEScopy InChI
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177036(CHEMBL1528007)copy SMILEScopy InChI
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Janssen Research& Development

Curated by ChEMBL
LigandPNGBDBM50177045(CHEMBL3814733)copy SMILEScopy InChI
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177035(CHEMBL3814774)copy SMILEScopy InChI
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
LigandPNGBDBM50177034(CHEMBL3813732)copy SMILEScopy InChI
Affinity DataIC50: 8.51E+3nMAssay Description:Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN46ZFPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121285((S)-2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121281(1-[2-(5-Propyl-1H-imidazol-2-yl)-2,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121278(3-Ethyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed