Compile Data Set for Download or QSAR
Found 1277 with Last Name = 'bogucki' and Initial = 'de'
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526223(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-2,6-diflu...)copy SMILES
Affinity DataIC50: 1nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526223(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-2,6-diflu...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526220(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-3-chloro-...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526197(4-((2-(azetidin-1-ylmethyl)-6-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526227(5-chloro-2-fluoro-4-(((6-fluoro-1H-indazol-7-yl)me...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526220(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-3-chloro-...)copy SMILES
Affinity DataIC50: 3nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526108(4-((2-(azetidin-1-ylmethyl)-3,6-difluorobenzyl)ami...)copy SMILES
Affinity DataIC50: 3nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525954(5-chloro-2-fluoro-4-((isoquinolin-8-ylmethyl)amino...)copy SMILES
Affinity DataIC50: 4nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525909(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-5-chloro-...)copy SMILES
Affinity DataIC50: 4nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526196(4-((2-(azetidin-1-ylmethyl)-6-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 7nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526197(4-((2-(azetidin-1-ylmethyl)-6-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 8nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525901((S)-5-chloro-4-((1-(5-chloro-2-fluorophenyl)ethyl)...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525934(5-chloro-2-fluoro-N-(thiazol-2-yl)-4-((3,3,3-trifl...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525940((S)-5-chloro-2-fluoro-4-((1-(2-fluorophenyl)propyl...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526161((S)-5-chloro-4-((1-(2,5-difluorophenyl)ethyl)amino...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526203(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-2,6-diflu...)copy SMILES
Affinity DataIC50: 10nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526062(2,6-difluoro-4-((2-fluoro-6-((3-hydroxy-3-methylaz...)copy SMILES
Affinity DataIC50: 11nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526203(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-2,6-diflu...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526183(4-((2-(azetidin-1-ylmethyl)-6-chlorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526176(4-((2-(azetidin-1-ylmethyl)-3,6-difluorobenzyl)ami...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525920((S)-2,6-difluoro-4-((1-(2-fluorophenyl)ethyl)amino...)copy SMILES
Affinity DataIC50: 12nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526081(4-((2-(azetidin-1-ylmethyl)-6-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 12nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525938((S)-5-chloro-2-fluoro-4-((1-(2-fluorophenyl)ethyl)...)copy SMILES
Affinity DataIC50: 13nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526206(4-((2-(azetidin-1-ylmethyl)-6-chloro-3-fluorobenzy...)copy SMILES
Affinity DataIC50: 14nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526059(2,6-difluoro-4-((2-fluoro-6-(pyrrolidin-1-ylmethyl...)copy SMILES
Affinity DataIC50: 15nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525971(Synthesis of(S)-5-chloro-4-((1-(2-chlorophenyl)eth...)copy SMILES
Affinity DataIC50: 15nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526159((S)-5-chloro-2-fluoro-4-((1-(2-fluorophenyl)ethyl)...)copy SMILES
Affinity DataIC50: 15nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526085(4-((2-(azetidin-1-ylmethyl)-6-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 15nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526046(4-((2-((2-oxa-6-azaspiro[3.3]heptan-6-yl)methyl)-6...)copy SMILES
Affinity DataIC50: 16nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526163((R)-5-chloro-4-((1-(5-chloro-2-fluorophenyl)-2,2,2...)copy SMILES
Affinity DataIC50: 18nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526158((S)-5-chloro-2-fluoro-N-(5-fluorothiazol-2-yl)-4-(...)copy SMILES
Affinity DataIC50: 18nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525942((S)-5-chloro-2-fluoro-4-((1-(3-fluorophenyl)ethyl)...)copy SMILES
Affinity DataIC50: 19nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526079(4-((2-((5-azaspiro[2.3]hexan-5-yl)methyl)-6-fluoro...)copy SMILES
Affinity DataIC50: 19nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526106(4-((2-(azetidin-1-ylmethyl)-3,6-difluorobenzyl)ami...)copy SMILES
Affinity DataIC50: 21nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525954(5-chloro-2-fluoro-4-((isoquinolin-8-ylmethyl)amino...)copy SMILES
Affinity DataIC50: 21nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526108(4-((2-(azetidin-1-ylmethyl)-3,6-difluorobenzyl)ami...)copy SMILES
Affinity DataIC50: 21nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526049(4-((2-((1-oxa-6-azaspiro[3.3]heptan-6-yl)methyl)-6...)copy SMILES
Affinity DataIC50: 22nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526012((S)-5-chloro-4-(1-(2,6-difluorophenyl)ethoxy)-2-fl...)copy SMILES
Affinity DataIC50: 23nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525925((S)-3-chloro-4-((1-phenylpropyl)amino)-N-(1,2,4-th...)copy SMILES
Affinity DataIC50: 23nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526090(4-((2-(azetidin-1-ylmethyl)-3-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 23nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526065(2,6-difluoro-4-((2-fluoro-6-((3-methoxy-3-methylaz...)copy SMILES
Affinity DataIC50: 23nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525933((S)-5-chloro-2-fluoro-4-((1-phenylpropyl)amino)-N-...)copy SMILES
Affinity DataIC50: 24nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50530541(CHEMBL4468899 | US11174268, Example 38)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526081(4-((2-(azetidin-1-ylmethyl)-6-fluorobenzyl)amino)-...)copy SMILES
Affinity DataIC50: 25nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526168((S)-4-((1-(5-chloro-2-fluorophenyl)ethyl)amino)-2-...)copy SMILES
Affinity DataIC50: 25nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525947((S)-5-chloro-2-fluoro-N-(thiazol-2-yl)-4-((1-(o-to...)copy SMILES
Affinity DataIC50: 25nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525902(Synthesis of(S)-3-chloro-2-fluoro-4-((1-(2-fluorop...)copy SMILES
Affinity DataIC50: 26nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525998(5-chloro-2-fluoro-4-((1-phenylcyclobutyl)amino)-N-...)copy SMILES
Affinity DataIC50: 27nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM526036(5-chloro-2-fluoro-4-(3-methyl-1-phenylbutylamino)-...)copy SMILES
Affinity DataIC50: 27nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM525936(5-chloro-2-fluoro-4-((1-phenylcyclopropyl)amino)-N...)copy SMILES
Affinity DataIC50: 28nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8X18US Patent
Displayed 1 to 50 (of 1277 total ) | Next | Last >>
Jump to: