Compile Data Set for Download or QSAR
Found 212 with Last Name = 'moore' and Initial = 'de'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086246(CHEMBL3425758)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086249(CHEMBL3425755)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086248(CHEMBL3425756)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086250(CHEMBL3425759)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086252(CHEMBL3425762)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086247(CHEMBL3425757)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086251(CHEMBL3425760)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086245(CHEMBL3425761)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341309(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341310(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341310(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50086253(CHEMBL3425763)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4CZWPubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341310(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)copy SMILEScopy InChI
Affinity DataKi:  125nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341310(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)copy SMILEScopy InChI
Affinity DataKi:  125nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341309(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341312((1R,5R,8R)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)copy SMILEScopy InChI
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341311((+/-)-isopropyl 8-(5-methyl-6-(2-methylpyridin-3-y...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50341313((1S,5S,8S)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)copy SMILEScopy InChI
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37G0PubMed
LigandPNGBDBM50344013(CHEMBL1780094 | trans-(3R,5S)-N-((6-aminopyridin-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344014(CHEMBL1779987 | trans-(3R,5S)-1-((5-methyl-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344015(CHEMBL1780096 | trans-(3S,5S)-5-ethyl-1-((5-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.955nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439646(CHEMBL2419600 | US8993586, 110)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344018(CHEMBL1779984 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439646(CHEMBL2419600 | US8993586, 110)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344017(1-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344019(CHEMBL1780085 | trans-(3R,5R)-5-(methoxymethyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.96nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439642(CHEMBL2419589 | US8993586, 105)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344020(CHEMBL1780116 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.91nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439644(CHEMBL2419593 | US8993586, 86)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344021(CHEMBL1779988 | trans-(3R,5R)-5-(methoxymethyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344022(CHEMBL1780100 | trans-(3S,5S)-5-(3-methyl-1,2,4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3.86nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344023(CHEMBL1780089 | trans-(3R,5R)-5-(3-methyl-1,2,4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439634(CHEMBL2419596 | US8993586, 71)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50259015(5-(3-chlorobenzyl)-3-isopropyl-1H-pyrazolo[4,3-d]p...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PDE1cMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74GGPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439643(CHEMBL2419598 | US8993586, 76)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439641(CHEMBL2419597 | US8993586, 55)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344024(CHEMBL1780097 | trans-(3S,5S)-5-(methoxymethyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344025(CHEMBL1780105 | trans-(3R,5R)-5-(methoxymethyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.36nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
LigandPNGBDBM50344026(CHEMBL1780111 | trans-(3R,5R)-N-((6-aminopyridin-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.42nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439645(CHEMBL2419607)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439642(CHEMBL2419589 | US8993586, 105)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439635(CHEMBL2419594 | US8993586, 88)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344027(CHEMBL1779985 | trans-(3R,5R)-1-((5-methyl-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439643(CHEMBL2419598 | US8993586, 76)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439638(CHEMBL2419599 | US8993586, 82)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439633(CHEMBL2419604)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
LigandPNGBDBM50344018(CHEMBL1779984 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20002F8PubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50439639(CHEMBL2419591 | US8993586, 64)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G9DPubMed
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