Compile Data Set for Download or QSAR
Found 35 with Last Name = 'doyle' and Initial = 'df'
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492417(CHEMBL2401843)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492420(CHEMBL2401846)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492417(CHEMBL2401843)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492420(CHEMBL2401846)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492421(CHEMBL2401845)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMedDrugBank
TargetEstrogen receptor(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492421(CHEMBL2401845)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492422(CHEMBL2401844)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492419(CHEMBL2401848)copy SMILEScopy InChI
Affinity DataIC50: 248nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492422(CHEMBL2401844)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492420(CHEMBL2401846)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492419(CHEMBL2401848)copy SMILEScopy InChI
Affinity DataIC50: 524nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492419(CHEMBL2401848)copy SMILEScopy InChI
Affinity DataIC50: 567nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492416(CHEMBL2401847)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492418(CHEMBL2401849)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492421(CHEMBL2401845)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492422(CHEMBL2401844)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492416(CHEMBL2401847)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492417(CHEMBL2401843)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50492416(CHEMBL2401847)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  42nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  26nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  7nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  36nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)copy SMILEScopy InChI
Affinity DataKd:  13nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289146XPubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)copy SMILEScopy InChI
Affinity DataKd:  40nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289146XPubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  51nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetDimer of Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  28nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetDimer of Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)copy SMILEScopy InChI
Affinity DataKd:  30nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289146XPubMed