Compile Data Set for Download or QSAR
Found 11 with Last Name = 'aitken' and Initial = 'dj'
TargetSubstance-P receptor(Homo sapiens (Human))
Laboratoire de Chimie Thérapeutique associé au CNRS et à l'Université René Descartes (UMR 8638)

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards Tachykinin receptor 1 expressed in CHO cells using [3H]-[Pro9]-SP as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CJ8CR0PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Laboratoire de Chimie Thérapeutique associé au CNRS et à l'Université René Descartes (UMR 8638)

Curated by ChEMBL
LigandPNGBDBM50097646((2-Methoxy-benzyl)-[1-(methylamino-phenyl-methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Binding affinity towards Tachykinin receptor 1 expressed in CHO cells using [3H]-[Pro9]-SP as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CJ8CR0PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Laboratoire de Chimie Thérapeutique associé au CNRS et à l'Université René Descartes (UMR 8638)

Curated by ChEMBL
LigandPNGBDBM50097647((3,5-Bis-trifluoromethyl-benzyl)-[1-(methylamino-p...)copy SMILEScopy InChI
Affinity DataKi:  620nMAssay Description:Binding affinity towards Tachykinin receptor 1 expressed in CHO cells using [3H]-[Pro9]-SP as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CJ8CR0PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197104((2S,1'R,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197104((2S,1'R,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed