Compile Data Set for Download or QSAR
Found 108 with Last Name = 'hoffman' and Initial = 'dj'
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230127(CHEMBL407606)copy SMILEScopy InChI
Affinity DataKi:  0.0245nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230129(CHEMBL407123)copy SMILEScopy InChI
Affinity DataKi:  0.0427nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230120(CHEMBL405737)copy SMILEScopy InChI
Affinity DataKi:  0.0776nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230123(CHEMBL385042)copy SMILEScopy InChI
Affinity DataKi:  0.0933nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230122(CHEMBL415571)copy SMILEScopy InChI
Affinity DataKi:  0.155nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230126(CHEMBL385468)copy SMILEScopy InChI
Affinity DataKi:  0.186nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230124(CHEMBL429240)copy SMILEScopy InChI
Affinity DataKi:  0.209nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230128(CHEMBL437798)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230130(CHEMBL266205)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230121(CHEMBL217405)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230125(CHEMBL274682)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50230119(CHEMBL414071)copy SMILEScopy InChI
Affinity DataKi:  9.30nMAssay Description:Negative logarithm of equilibrium dissociation constant in the rat pituitary luteinizing releasing hormone receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X6MPubMed
LigandPNGBDBM50080742((S)-2-[(5-{[Benzyl-(5-fluoro-pyridin-3-yl)-amino]-...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080765((S)-2-({5-[(Cyclohexylmethyl-pyridin-3-yl-amino)-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080764((S)-2-({5-[(Benzyl-pyridin-3-yl-amino)-methyl]-2'-...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080748((S)-2-[(5-{[(3,5-Difluoro-benzyl)-thiazol-5-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080743((S)-2-({5-[(Benzyl-thiazol-5-ylmethyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017780(CHEMBL284451 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017780(CHEMBL284451 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 6.0Assay Description:Inhibitory activity against purified human renal renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080747((S)-2-[(5-{[(3,5-Difluoro-benzyl)-phenyl-amino]-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50067581((S)-2-{[2'-Methyl-5-(pyridin-3-ylaminomethyl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080750((S)-2-({5-[(Benzyl-pyrimidin-5-yl-amino)-methyl]-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080759((S)-2-{[2'-Methyl-4-phenethyl-5-(pyridin-3-yloxyme...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017783(CHEMBL440779 | N-{1-[1-(4-Azido-1-cyclohexylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017783(CHEMBL440779 | N-{1-[1-(4-Azido-1-cyclohexylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017782(CHEMBL280744 | Tetrahydro-pyran-4-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
LigandPNGBDBM50080744((S)-2-({5-[(Benzyl-pyrazin-2-yl-amino)-methyl]-2'-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080762((S)-2-{[4-Benzyl-2'-methyl-5-(pyridin-3-yloxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080745((S)-2-({5-[(Benzyl-phenyl-amino)-methyl]-2'-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080763((S)-2-[(5-{[(3,5-Difluoro-benzyl)-pyridin-3-yl-ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050056(2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB80WGPubMed
LigandPNGBDBM50080761((S)-2-{[2'-Methyl-4-pentyl-5-(pyridin-3-yloxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017777(CHEMBL281436 | N-[1-[1-(4-Azido-1-cyclohexylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 6.0Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017778(CHEMBL282757 | Morpholine-4-carboxylic acid {1-[1-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017778(CHEMBL282757 | Morpholine-4-carboxylic acid {1-[1-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.4Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
LigandPNGBDBM50080760((S)-2-{[4-Ethyl-2'-methyl-5-(pyridin-3-yloxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017773(CHEMBL280503 | Morpholine-4-carboxylic acid [1-[1-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 6.0Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050063(2-[(R)-1-[(S)-2-(Cyclohexyl-methyl-carbamoyloxy)-4...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB80WGPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017774(CHEMBL29004 | {1-[1-(4-Azido-1-cyclohexylmethyl-2,...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMpH: 6.0Assay Description:Inhibitory activity against purified human renal renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017779(CHEMBL28679 | {1-[1-(4-Azido-1-cyclohexylmethyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMpH: 6.0Assay Description:Inhibitory activity against purified human renal renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
LigandPNGBDBM50080752((S)-2-({5-[(Benzyl-thiazol-2-ylmethyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
LigandPNGBDBM50080751((S)-2-({5-[(Benzenesulfonyl-pyridin-3-yl-amino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958DCPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017775(CHEMBL29315 | {1-[1-(3-Azido-1-cyclohexylmethyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMpH: 6.0Assay Description:Inhibitory activity against purified human renal renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017782(CHEMBL280744 | Tetrahydro-pyran-4-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMpH: 7.4Assay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017780(CHEMBL284451 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050058(2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pe...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB80WGPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017786(CHEMBL408084 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 6.0Assay Description:Inhibitory activity against purified human renal renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50017777(CHEMBL281436 | N-[1-[1-(4-Azido-1-cyclohexylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BFRPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050047(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB80WGPubMed
Displayed 1 to 50 (of 108 total ) | Next | Last >>
Jump to: