Compile Data Set for Download or QSAR
Found 275 with Last Name = 'hosfield' and Initial = 'dj'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264012(2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263974(2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263992(2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM50158627(CHEMBL3787482 | US10023592, Example 81)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM191600(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285038(4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263991(2-{5-[(4-ethylbenzyl)oxy]- 1H-pyrazol-1-yl}pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285038(4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264001(2-{5-[(4-chloro-2- fluorobenzyl)oxy]-1H-pyrazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263975(2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264021(2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] py...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263978(2-{5-[(4-methoxybenzyl)oxy]-1H- pyrazol-1-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50158703(CHEMBL3785832 | US10173996, Example 53 | US9604961...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263990(2-{5-[(4-methylbenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264030(2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM50158627(CHEMBL3787482 | US10023592, Example 81)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285167(2-methyl-6-(1-methylpyrazol-4-yl)-4-(5- methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263974(2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263992(2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM321348(3-({[(1R)-6-methoxy-1,2,3,4- tetrahydronaphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NPJPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264003(2-{5-[(4-cyclopropylbenzyl)oxy]- 1H-pyrazol-1-yl}p...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NPJPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285166(4-(2-ethoxy-5-methylsulfonylphenyl)-2- methyl-6-(1...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285167(2-methyl-6-(1-methylpyrazol-4-yl)-4-(5- methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NPJPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264012(2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NPJPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM191600(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50158703(CHEMBL3785832 | US10173996, Example 53 | US9604961...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285034(4-(5-ethylsulfonyl-2-methoxyphenyl)-2- methyl-6-(1...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50457156(CHEMBL4207071)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NPJPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285039(4-[5-ethylsulfonyl-2-(2- hydroxyethoxy)phenyl]-2-m...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264001(2-{5-[(4-chloro-2- fluorobenzyl)oxy]-1H-pyrazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264030(2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263976(2-{5-[(3-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264007(2-[4-ethyl-5-[(4- fluorophenyl)methoxy]pyrazol-1- ...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263975(2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285166(4-(2-ethoxy-5-methylsulfonylphenyl)-2- methyl-6-(1...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75WNPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264007(2-[4-ethyl-5-[(4- fluorophenyl)methoxy]pyrazol-1- ...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM264021(2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] py...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM263990(2-{5-[(4-methylbenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NPJPubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM191600(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20W4PubMed
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