Found 41 with Last Name = 'o''mahony' and Initial = 'dj' TargetTransient receptor potential cation channel subfamily V member 4(Mus musculus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Mus musculus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.94E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.11E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.17E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.92E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.22E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.93E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 5.74E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 6.49E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 8.53E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human TRPV3 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in HEK293 cells assessed as inhibition of menthol-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
