Compile Data Set for Download or QSAR
Found 154 with Last Name = 'spalding' and Initial = 'dj'
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50160917(3-(3-(2-(benzyloxy)-5-chlorophenyl)thiophen-2-yl)b...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Antagonist activity against PGE2 activated EP1 receptor assessed as ability to inhibit intracellular calcium mobilisation by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J102RMPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17156(3-(4-{[3-(3-methoxy-4-{[(2-methylphenyl)carbamoyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.5nM ΔG°:  -52.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17175((3R)-3-(4-{[3-(2-chloro-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  0.790nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17169((3R)-3-(4-{[3-(3-methoxy-4-{[(2-methylphenyl)carba...)copy SMILEScopy InChI
Affinity DataKi:  0.790nM ΔG°:  -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17174((3R)-3-(4-{[3-(3-methyl-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17170((3R)-3-(4-{[3-(3-chloro-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17168((3S)-3-(4-{[3-(3-methoxy-4-{[(2-methylphenyl)carba...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17167((3R)-3-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17154(3-{4-[(3-{3-methoxy-4-[(phenylcarbamoyl)amino]phen...)copy SMILEScopy InChI
Affinity DataKi:  1.58nM ΔG°:  -49.7kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17172((3R)-3-(4-{[3-(3-ethoxy-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17164(3-(4-{[3-(4-{[(2,6-dimethylphenyl)carbamoyl]amino}...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17177((3S)-3-(4-{[3-(3-chloro-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17166((3S)-3-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino...)copy SMILEScopy InChI
Affinity DataKi:  2.51nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17165(3-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino}phen...)copy SMILEScopy InChI
Affinity DataKi:  2.51nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17176((3R)-3-(4-{[3-(2-methyl-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17181((3S)-3-(4-{[3-(3-methyl-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17171((3R)-3-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino...)copy SMILEScopy InChI
Affinity DataKi:  3.98nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17159(3-(4-{[3-(4-{[(2-bromophenyl)carbamoyl]amino}-3-me...)copy SMILEScopy InChI
Affinity DataKi:  5.01nM ΔG°:  -46.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17179((3S)-3-(4-{[3-(3-ethoxy-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17173((3R)-3-(4-{[3-(3-ethyl-4-{[(2-methylphenyl)carbamo...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17158(3-(4-{[3-(3-methoxy-4-{[(2-methoxyphenyl)carbamoyl...)copy SMILEScopy InChI
Affinity DataKi:  6.31nM ΔG°:  -46.3kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17160(3-(4-{[3-(4-{[(2-acetamidophenyl)carbamoyl]amino}-...)copy SMILEScopy InChI
Affinity DataKi:  6.31nM ΔG°:  -46.3kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17163(3-(4-{[3-(4-{[(2,5-dimethylphenyl)carbamoyl]amino}...)copy SMILEScopy InChI
Affinity DataKi:  7.94nM ΔG°:  -45.8kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17183((3S)-3-(4-{[3-(2-methyl-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  19.9nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17178((3S)-3-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino...)copy SMILEScopy InChI
Affinity DataKi:  19.9nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17161(3-(4-{[3-(4-{[(2,3-dimethylphenyl)carbamoyl]amino}...)copy SMILEScopy InChI
Affinity DataKi:  25.1nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17182((3S)-3-(4-{[3-(2-chloro-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17162(3-(4-{[3-(4-{[(2,4-dimethylphenyl)carbamoyl]amino}...)copy SMILEScopy InChI
Affinity DataKi:  25.1nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461458(CHEMBL4229200)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17180((3S)-3-(4-{[3-(3-ethyl-4-{[(2-methylphenyl)carbamo...)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461462(CHEMBL4225786)copy SMILEScopy InChI
Affinity DataKi:  79nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461457(CHEMBL4225963)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461454(CHEMBL4224936)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461450(CHEMBL4226720)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17157(3-[4-({3-[3-methoxy-4-({[2-(propan-2-yl)phenyl]car...)copy SMILEScopy InChI
Affinity DataKi:  316nM ΔG°:  -36.7kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7S8VPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461451(CHEMBL4226523)copy SMILEScopy InChI
Affinity DataKi:  398nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461463(CHEMBL4225442)copy SMILEScopy InChI
Affinity DataKi:  631nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461453(CHEMBL4226984)copy SMILEScopy InChI
Affinity DataKi:  631nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461468(CHEMBL4227243)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50461456(CHEMBL4228095)copy SMILEScopy InChI
Affinity DataKi: <6.31E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z472WPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50422961(CHEMBL387969)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HV3PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50422978(CHEMBL228586)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HV3PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423023(CHEMBL427844)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91B9PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423034(CHEMBL390189)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91B9PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50422971(CHEMBL387878)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HV3PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50422986(CHEMBL228593)copy SMILEScopy InChI
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HV3PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423041(CHEMBL430360)copy SMILEScopy InChI
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91B9PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423032(CHEMBL234727)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91B9PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50422973(CHEMBL395248)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HV3PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423044(CHEMBL234519)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91B9PubMed
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