Compile Data Set for Download or QSAR
Found 186 with Last Name = 'kancharla' and Initial = 'dm'
LigandPNGBDBM50403292(CHEMBL5285364)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50391288(CHEMBL5288438)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50456116(Prx-03140)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50391287(CHEMBL5278176)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50391258(CHEMBL5286257)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
LigandPNGBDBM50456112(CHEMBL4215911)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
LigandPNGBDBM325596(3-[5-(1-Cyclobutyl-piperidin-4-yl)-[1,3,4]oxadiazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50391298(CHEMBL5275605)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391288(CHEMBL5288438)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig left atriaMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM325561(1-Isopropyl-3-{5-[1-(3-methoxy propyl) piperidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM325602(1-Isopropyl-3-{5-[1-(tetrahydro-pyran-4-ylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391267(CHEMBL5289747)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM325561(1-Isopropyl-3-{5-[1-(3-methoxy propyl) piperidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50456112(CHEMBL4215911)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins in presence of NADPH-regeneration system by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50456112(CHEMBL4215911)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins in presence of NADPH-regeneration system by LC-MS/MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins in presence of NADPH-regeneration system by LC-MS/MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
LigandPNGBDBM50391283(CHEMBL5268064)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for inhibitory activity against rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins in presence of NADPH-regeneration system by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
LigandPNGBDBM50391246(CHEMBL5275895)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat microsomal HMG-CoA reductase activity by 50%More data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391281(CHEMBL5286642)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391281(CHEMBL5286642)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig right atriaMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391266(CHEMBL5271080)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391278(CHEMBL5274204)copy SMILEScopy InChI
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM325598(3-[5-(1-Cyclopropylmethyl-piperidin-4-yl)-[1,3,4]o...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig left atriaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391265(CHEMBL5276171)copy SMILEScopy InChI
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM325596(3-[5-(1-Cyclobutyl-piperidin-4-yl)-[1,3,4]oxadiazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig right atriaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50403292(CHEMBL5285364)copy SMILEScopy InChI
Affinity DataIC50: 3.77E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-2 adrenergic receptor from guinea pig trachea.More data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391246(CHEMBL5275895)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391248(CHEMBL5284140)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM325597(1-Isopropyl-3-[5-(1-isopropyl-piperidin-4-yl)-[1,3...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM325594(3-[5-(1-Cyclobutylmethyl-piperidin-4-yl)-[1,3,4]ox...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM325598(3-[5-(1-Cyclopropylmethyl-piperidin-4-yl)-[1,3,4]o...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM325596(3-[5-(1-Cyclobutyl-piperidin-4-yl)-[1,3,4]oxadiazo...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391283(CHEMBL5268064)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM325602(1-Isopropyl-3-{5-[1-(tetrahydro-pyran-4-ylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391288(CHEMBL5288438)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50391298(CHEMBL5275605)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM50403292(CHEMBL5285364)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391246(CHEMBL5275895)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391248(CHEMBL5284140)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Evaluated for inhibitory activity against rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391265(CHEMBL5276171)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391266(CHEMBL5271080)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rabbit lung angiotensin I converting enzyme (ACE) using hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391267(CHEMBL5289747)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Antagonistic activity against Thromboxane A2 receptor in guinea pig trachea in the presence of 11,9-epoxymethano-PGH2More data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391278(CHEMBL5274204)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig right atriaMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM325597(1-Isopropyl-3-[5-(1-isopropyl-piperidin-4-yl)-[1,3...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig right atriaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM325594(3-[5-(1-Cyclobutylmethyl-piperidin-4-yl)-[1,3,4]ox...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig left atriaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50391283(CHEMBL5268064)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig left atriaMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM325561(1-Isopropyl-3-{5-[1-(3-methoxy propyl) piperidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig right atriaMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM325602(1-Isopropyl-3-{5-[1-(tetrahydro-pyran-4-ylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-1 adrenergic receptor from guinea pig left atriaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
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