Compile Data Set for Download or QSAR
Found 88 with Last Name = 'korzhnev' and Initial = 'dm'
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463119(CHEMBL4240676)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463115(CHEMBL1717725)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463120(CHEMBL1721787)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463107(CHEMBL4245882)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463117(CHEMBL4249624)copy SMILEScopy InChI
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463116(CHEMBL4237457)copy SMILEScopy InChI
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463122(CHEMBL4249812)copy SMILEScopy InChI
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463118(CHEMBL4246571)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463106(CHEMBL4238011)copy SMILEScopy InChI
Affinity DataKi:  6.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463105(CHEMBL4244254)copy SMILEScopy InChI
Affinity DataKi:  7.40E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463108(CHEMBL4244874)copy SMILEScopy InChI
Affinity DataKi:  8.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463113(CHEMBL4238016)copy SMILEScopy InChI
Affinity DataKi:  1.16E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463114(CHEMBL4241371)copy SMILEScopy InChI
Affinity DataKi:  1.19E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463103(CHEMBL4237396)copy SMILEScopy InChI
Affinity DataKi:  1.45E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463123(CHEMBL4239688)copy SMILEScopy InChI
Affinity DataKi:  1.48E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463111(CHEMBL4239342)copy SMILEScopy InChI
Affinity DataKi:  1.57E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463109(CHEMBL4241418)copy SMILEScopy InChI
Affinity DataKi:  1.90E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463112(CHEMBL4249428)copy SMILEScopy InChI
Affinity DataKi:  2.88E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463104(CHEMBL4242335)copy SMILEScopy InChI
Affinity DataKi:  3.15E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463110(CHEMBL2136004)copy SMILEScopy InChI
Affinity DataKi:  4.66E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA polymerase iota(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase eta(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant DNA polymerase eta expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at 2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase eta(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant DNA polymerase eta expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at 2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase iota(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191328(CHEMBL3937487)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition by fluorescence-based HTS ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191343(CHEMBL3967184)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition by fluorescence-based HTS ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetProliferating cell nuclear antigen(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50431467(CHEMBL2348305)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to full length human PCNA expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with N-terminal 5-carboxyflu...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463106(CHEMBL4238011)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463117(CHEMBL4249624)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463119(CHEMBL4240676)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463115(CHEMBL1717725)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463107(CHEMBL4245882)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463116(CHEMBL4237457)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463108(CHEMBL4244874)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463114(CHEMBL4241371)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50099491(2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463120(CHEMBL1721787)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191327(CHEMBL3960997)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463113(CHEMBL4238016)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463118(CHEMBL4246571)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA repair protein REV1(Homo sapiens)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50463122(CHEMBL4249812)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93B5HPubMed
TargetDNA polymerase iota(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human DNA polymerase iota preincubated for 15 mins followed by replicating non-damaged DNA substrate addition measured after 30 mins in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM79172(2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenyli...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
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