Compile Data Set for Download or QSAR
Found 102 with Last Name = 'nason' and Initial = 'dm'
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032162(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,7-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032161(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-7-methyl-5,7...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032164(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5,6-dihydroiso...)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032163(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5H-isoxazolo[5...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255776(CHEMBL4075310)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032165(CHEMBL92736 | CHEMBL94217 | N-{3-[2-(1-Benzyl-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255775(CHEMBL4079080)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032160(3-(2-(1-benzylpiperidin-4-yl)ethyl)-6H-isoxazolo[5...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255806(CHEMBL4097100)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255777(CHEMBL4061795)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMedDrugBank
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255777(CHEMBL4061795)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255805(CHEMBL4086931)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255786(CHEMBL4076777)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150885(6-(4-Dimethylaminomethyl-5-ethyl-2-methoxy-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150887(6-[4-(2-Dimethylamino-ethoxy)-5-ethyl-2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human serumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150884(6-[4-(3-Dimethylamino-propyl)-5-ethyl-2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150890(6-[4-(2-Dimethylamino-ethyl)-5-ethyl-2-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150883(6-[4-(2-Dimethylamino-ethoxy)-2,5-dimethoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255814(CHEMBL4059563)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50081082(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150888(6-[4-(3-Dimethylamino-propyl)-2,5-dimethoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150886(6-[4-(2-Dimethylamino-ethyl)-2,5-dimethoxy-phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 235nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255813(CHEMBL4092367)copy SMILEScopy InChI
Affinity DataIC50: 242nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255808(CHEMBL4068209)copy SMILEScopy InChI
Affinity DataIC50: 354nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255787(CHEMBL4104811)copy SMILEScopy InChI
Affinity DataIC50: 445nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255810(CHEMBL4081518)copy SMILEScopy InChI
Affinity DataIC50: 582nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150889(6-(4-Dimethylaminomethyl-2,5-dimethoxy-phenyl)-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50081082(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)copy SMILEScopy InChI
Affinity DataIC50: 887nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255807(CHEMBL4089392)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255787(CHEMBL4104811)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255805(CHEMBL4086931)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255808(CHEMBL4068209)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032160(3-(2-(1-benzylpiperidin-4-yl)ethyl)-6H-isoxazolo[5...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50240693(CHEMBL4097569)copy SMILEScopy InChI
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of PDE2A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93Q2PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255775(CHEMBL4079080)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255786(CHEMBL4076777)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150887(6-[4-(2-Dimethylamino-ethoxy)-5-ethyl-2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032163(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5H-isoxazolo[5...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032164(3-(2-(1-benzylpiperidin-4-yl)ethyl)-5,6-dihydroiso...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.

Curated by ChEMBL
LigandPNGBDBM50255776(CHEMBL4075310)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VD4PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032161(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-7-methyl-5,7...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
LigandPNGBDBM50240693(CHEMBL4097569)copy SMILEScopy InChI
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of PDE11A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93Q2PubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50032162(3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,7-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150884(6-[4-(3-Dimethylamino-propyl)-5-ethyl-2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50150885(6-(4-Dimethylaminomethyl-5-ethyl-2-methoxy-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 8.83E+3nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase in humanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QP6PubMed
Displayed 1 to 50 (of 102 total ) | Next | Last >>
Jump to: