Compile Data Set for Download or QSAR
Found 115 with Last Name = 'matthews' and Initial = 'dp'
TargetAdenosylhomocysteinase(Mus musculus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50280299((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)copy SMILEScopy InChI
Affinity DataKi:  550nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Mus musculus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50280301((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)copy SMILEScopy InChI
Affinity DataKi:  1.04E+3nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280298((1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Tested for binding affinity of compound against S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VDD
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368169(CHEMBL2368687)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as Kinactivator values; NA= not applicableMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368167(CHEMBL3349334 | CHEMBL611905)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as Kinactivator values; NA= not applicableMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280301((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368170(CHEMBL2368677)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibitory activity against rat liver S-Adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50406477(CHEMBL2051968 | CHEMBL2069133)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibitory activity against rat liver S-Adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280299((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280300((1R,2S,3R)-3-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)copy SMILEScopy InChI
Affinity DataKi:  6.90E+3nMAssay Description:Tested for binding affinity of compound against S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VDD
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368168(CHEMBL609353)copy SMILEScopy InChI
Affinity DataKi:  9.70E+3nMAssay Description:Competitive inhibitory activity against rat liver S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368168(CHEMBL609353)copy SMILEScopy InChI
Affinity DataKi:  9.70E+3nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as Kinactivator values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Mus musculus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50368168(CHEMBL609353)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50229043(CHEMBL2051969)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Competitive inhibitory activity against rat liver S-Adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Mus musculus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50144936(CHEMBL1090 | VIDARABINE | adenine arabinoside)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetAdenosylhomocysteinase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50011352(5-(6-Amino-purin-9-yl)-2-fluoromethylene-tetrahydr...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nMAssay Description:Activity determined in rat liver S-adenosyl-L-homocysteine hydrolase and expressed as Kinactivator values; NA= not applicableMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M6695PubMed
TargetCathepsin S(Mus musculus (Mouse))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030823(CHEMBL3342553)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GXNPubMed
TargetCathepsin S(Mus musculus (Mouse))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030822(CHEMBL3342554)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GXNPubMed
TargetCathepsin S(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030823(CHEMBL3342553)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030822(CHEMBL3342554)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GXNPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195711(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195708(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195714(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195716(3-{4-[2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195702(3-[4-[2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195715(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195713(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195711(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195707(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195710(3-(2-((benzyloxycarbonyl)methyl)-4-(2-(5-methyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015622(1-(2-Thiophen-2-yl-ethyl)-1,3-dihydro-imidazole-2-...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W094XVPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015620(1-(2-Thiophen-3-yl-ethyl)-1,3-dihydro-imidazole-2-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W094XVPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195714(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195712(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 161nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W094XVPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195710(3-(2-((benzyloxycarbonyl)methyl)-4-(2-(5-methyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 441nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195716(3-{4-[2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 449nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015617(1-[2-(5-Methyl-thiophen-2-yl)-ethyl]-1,3-dihydro-i...)copy SMILEScopy InChI
Affinity DataIC50: 491nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W094XVPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195715(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 516nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195709(3-(2-((3-benzylureido)methyl)-4-(2-(5-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataIC50: 706nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015621(1-(5-Chloro-thiophen-2-ylmethyl)-1,3-dihydro-imida...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W094XVPubMed
TargetCathepsin S(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030816(CHEMBL3342550)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GXNPubMed
TargetCathepsin S(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030817(CHEMBL3342551)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195708(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetCathepsin S(Mus musculus (Mouse))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030816(CHEMBL3342550)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GXNPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50015619(1-(3-Thiophen-2-yl-propyl)-1,3-dihydro-imidazole-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W094XVPubMed
TargetCathepsin S(Mus musculus (Mouse))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030817(CHEMBL3342551)copy SMILEScopy InChI
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of mouse cathepsin S using benzyloxycarbonyl-L-Leucyl-L-Arginine 4-Methyl-coumaryl-7-amide substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GXNPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50241379((enoximone)4-Methyl-5-(4-methylsulfanyl-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of canine heart Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7R0GPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195707(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 3.39E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
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