Compile Data Set for Download or QSAR
Found 960 with Last Name = 'greve' and Initial = 'dr'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536220(CHEMBL4528395)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536208(CHEMBL4483364)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536217(CHEMBL4517645)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536209(CHEMBL4539949)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536200(CHEMBL4483513)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536214(CHEMBL4560212)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536198(CHEMBL4534573)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536221(CHEMBL4554460)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536216(CHEMBL4580425)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536209(CHEMBL4539949)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536197(CHEMBL4521312)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536215(CHEMBL4569613)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536208(CHEMBL4483364)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536198(CHEMBL4534573)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536204(CHEMBL4563039)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536208(CHEMBL4483364)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536200(CHEMBL4483513)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536205(CHEMBL4543715)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536198(CHEMBL4534573)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536217(CHEMBL4517645)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536222(CHEMBL4531121)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536214(CHEMBL4560212)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536209(CHEMBL4539949)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536212(CHEMBL4551061)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536217(CHEMBL4517645)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536218(CHEMBL4516561)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536221(CHEMBL4554460)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536215(CHEMBL4569613)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
LigandPNGBDBM547772((R)-2-(3-Phenylazetidin-1-yl)-4-((tetrahydro-2H-py...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547773((R)-2-(3-Phenoxyazetidin-1-yl)-4-((tetrahydro-2H-p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547774((R)-2-(3-(4-Fluorophenoxy)azetidin-1-yl)-4-((tetra...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547776(Methyl (3R)-3-(((5R)-5-Oxido-2-(3-phenylazetidin-1...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547777(Methyl (3R)-3-(((5R)-2-(3-(4-Fluorophenoxy)azetidi...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547778(Methyl (3S)-3-(((5R)-2-(3-(4-Fluorophenoxy)azetidi...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547779((R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-(4-flu...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547780((R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-(4-flu...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547781((R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-phenyl...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547783((R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-(3-flu...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547784((R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-(pyrid...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547785((R)-4-((1-Methylcyclobutyl)amino)-2-(3-(pyridin-2-...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM547787((5R)—N-(1,1-Dioxothian-4-yl)-5-oxido-2-(3-phe...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ697HUS Patent
LigandPNGBDBM560691(Methyl (3R)-3-[[(1R)-5-[3-(4-fluorophenyl)azetidin...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75KJ8US Patent
LigandPNGBDBM560692(Methyl (3R)-3-[[(1R)-5-(3-(4-phenylazetidin-1-yl)-...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75KJ8US Patent
LigandPNGBDBM560696(1-[(3S)-3-[[(1R)-5-[3-(4-Fluorophenoxy)azetidin-1-...)copy SMILES
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75KJ8US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536222(CHEMBL4531121)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536218(CHEMBL4516561)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536200(CHEMBL4483513)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536221(CHEMBL4554460)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536205(CHEMBL4543715)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Drug Design, In Vitro Biology, Skin PK and Early Safety, and Preformulation & Early Analytical Development, Global R&D, LEO Pharma A/S , Industriparken 55, DK-2750 Ballerup, Denmark.

Curated by ChEMBL
LigandPNGBDBM50536210(CHEMBL4518744)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC146JPubMed
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