Compile Data Set for Download or QSAR
Found 87 with Last Name = 'rose' and Initial = 'dr'
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84868(Swainsonine derivative, 3)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84869(Swainsonine derivative, 4)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84867(Swainsonine derivative, 2)copy SMILEScopy InChI
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327503((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ0411PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330961((2R,3S,4S)-1-((2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahyd...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330954(CHEMBL1276973 | de-O-sulfonated kotalanol)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50078117((1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTAN...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of human N-terminal maltase-glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ0411PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330960((2R,3R,4R)-1-((2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahyd...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50088625((1R,2R,3R,4S,5R)-4-Amino-5-methoxy-cyclopentane-1,...)copy SMILEScopy InChI
Affinity DataKi:  76nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330959(CHEMBL1277153)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50316180((1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8Z5JPubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)copy SMILEScopy InChI
Affinity DataKi:  103nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50316181((1S,2R,3S,4R)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8Z5JPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84614(Mannostatin B, 2)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ06T7PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327501(CHEMBL1258528 | ponkoranol)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ0411PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50316179((1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50316179((1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8Z5JPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50316178(1,4-Dideoxy-1,4-[[2S,3S,4R,5R,6R-2,4,5,6,7-pentahy...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8Z5JPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84615(Mannostatin analogue, 4a)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)copy SMILEScopy InChI
Affinity DataKi:  302nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant N-terminal maltase-glucoamylase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ0411PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of human N-terminal maltase-glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81DHZPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataKi:  550nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataKi:  670nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330955((1S,2S)-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymeth...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330957(7'-[(1,5-Dideoxy-1,5-imino-D-glucitol)-5-N-ammoniu...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330956(7'-[(1,5-Dideoxy-1,5-imino-D-glucitol)-5-N-ammoniu...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataKi:  2.33E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataKi:  3.25E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataKi:  4.15E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50330958((2R,3R,4R,5R,6S)-1-((2R,3R,4R)-3,4-dihydroxy-2-(hy...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RZHPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50088627((1S,2S,3R,4R)-4-Amino-cyclopentane-1,2,3-triol | (...)copy SMILEScopy InChI
Affinity DataKi:  2.65E+5nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84871(Swainsonine derivative, 6)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84872(Swainsonine derivative, 7)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84870(Swainsonine derivative, 5)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263091((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50067661(CHEMBL137706 | Phosphoric acid mono-(4-{(S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity for SH2 domain of src in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1K2KPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50067665(CHEMBL137715 | Phosphoric acid mono-(4-{(S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Affinity for SH2 domain of src in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1K2KPubMed
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