Compile Data Set for Download or QSAR
Found 40 with Last Name = 'fischer' and Initial = 'ds'
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370656(CHEMBL1627749)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172493((13S)-3-hydroxy-16-(hydroxymethylene)-13-methyl-7,...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172493((13S)-3-hydroxy-16-(hydroxymethylene)-13-methyl-7,...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172503((S)-6a-Methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahyd...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172503((S)-6a-Methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahyd...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172504((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370701(CHEMBL1627773)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370702(CHEMBL1627790)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM17289((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370698(CHEMBL1628005)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370695(CHEMBL1628021)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50366344(CHEMBL1627450)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50182496(2-hydroxy-6a-methyl-5,6,6a,8,10,10a,10b,11-octahyd...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370696(CHEMBL1627763)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172495((S)-8-(2-Methoxy-ethyl)-6a-methyl-4b,5,6,6a,8,10,1...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172499(3-((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172496((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370703(CHEMBL1627771)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172500((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172494(((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172502((S)-9-Hydroxymethyl-6a-methyl-4b,5,6,6a,8,10,10a,1...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370664(CHEMBL1627756)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370664(CHEMBL1627756)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370700(CHEMBL1628135)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172491((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370699(CHEMBL1627779)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172497((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50172501((S)-6a,8-Dimethyl-4b,5,6,6a,8,10,10a,10b,11,12-dec...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370697(CHEMBL1628134)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24X7JPubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Universit£ Joseph Fourier

Curated by ChEMBL
LigandPNGBDBM50324696(CHEMBL1221990 | Phenoxyacetyl lactivicin)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x after 60 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BK9PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Bath

Curated by ChEMBL
LigandPNGBDBM50370663(CHEMBL1627759)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7J38PubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50300661(3-borono-5-(2-methoxybenzamido)benzoic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50300664(3-borono-5-(2-phenoxyacetamido)benzoic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50300662(3-borono-5-(thiophene-2-carboxamido)benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50300660(3-benzamido-5-boronobenzoic acid | CHEMBL575719)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50300663(3-borono-5-(2-(thiophen-2-yl)acetamido)benzoic aci...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50300659(3-borono-5-(2-phenylacetamido)benzoic acid | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Universit£ Joseph Fourier

Curated by ChEMBL
LigandPNGBDBM50324697(CHEMBL1221989 | Lactivicin)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x after 120 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BK9PubMed
TargetD-alanyl-D-alanine carboxypeptidase(Actinomadura sp. (strain R39))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50067893(3-Carboxyphenylboronicacid | 3-boronobenzoic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Universit£ Joseph Fourier

Curated by ChEMBL
LigandPNGBDBM50300665(5-boronothiophene-2-carboxylic acid | CHEMBL573906)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate mixture of (R)-[2-(benzoyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DSSPubMed