Compile Data Set for Download or QSAR
Found 157 with Last Name = 'lala' and Initial = 'ds'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382321(CHEMBL2024688)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382322(CHEMBL2024689)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156246(US9018391, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150700(US8981112, 7 | US9526727, 7 | US9949975, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150700(US8981112, 7 | US9526727, 7 | US9949975, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382324(CHEMBL2024691)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150700(US8981112, 7 | US9526727, 7 | US9949975, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156243(US9018391, 5)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156242(US9018391, 4)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150705(US8981112, 12 | US9526727, 12 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156241(US9018391, 3)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150705(US8981112, 12 | US9526727, 12 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382320(CHEMBL2024687)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150705(US8981112, 12 | US9526727, 12 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156245(US9018391, 7)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150704(US8981112, 11 | US9526727, 11 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150704(US8981112, 11 | US9526727, 11 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382318(CHEMBL2024685)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382319(CHEMBL2024686)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150704(US8981112, 11 | US9526727, 11 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156252(US9018391, 14)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150697(US8981112, 4 | US9526727, 4)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150701(US8981112, 8 | US9526727, 8 | US9949975, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150707(US8981112, 14 | US9526727, 14 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150714(US8981112, 21 | US9526727, 21 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150717(US8981112, 24 | US9526727, 24 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150697(US8981112, 4 | US9526727, 4)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150701(US8981112, 8 | US9526727, 8 | US9949975, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150707(US8981112, 14 | US9526727, 14 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150714(US8981112, 21 | US9526727, 21 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150717(US8981112, 24 | US9526727, 24 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382325(CHEMBL2024693)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM389136(US9949975, Example 4)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150701(US8981112, 8 | US9526727, 8 | US9949975, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150707(US8981112, 14 | US9526727, 14 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150714(US8981112, 21 | US9526727, 21 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150717(US8981112, 24 | US9526727, 24 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150712(US8981112, 19 | US9526727, 19 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150720(US8981112, 27 | US9526727, 27 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150712(US8981112, 19 | US9526727, 19 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150720(US8981112, 27 | US9526727, 27 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382323(CHEMBL2024690)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150712(US8981112, 19 | US9526727, 19 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150720(US8981112, 27 | US9526727, 27 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156244(US9018391, 6)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM156250(US9018391, 12)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65HRUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150695(US8981112, 2 | US9526727, 2 | US9949975, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150698(US8981112, 5)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Boehringer Ingelheim International GmbH; Vitae Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM150715(US8981112, 22 | US9526727, 22 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent
TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical, Inc.

US Patent
LigandPNGBDBM150695(US8981112, 2 | US9526727, 2 | US9949975, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936GWUS Patent
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