Compile Data Set for Download or QSAR
Found 17 with Last Name = 'university of pennsylvania,' and Initial = 'dw'
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/mole IC50: 1.10nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198120(TSA)copy SMILEScopy InChI
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/mole IC50: 1.40nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198121(HPOB)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/mole IC50: 1.80nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/mole IC50: 1.90nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198124(Panobinostat)copy SMILEScopy InChI
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/mole IC50: 2.5nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [84-835](Homo sapiens (Human))
University of Pennsylvania,

LigandPNGBDBM198120(TSA)copy SMILEScopy InChI
Affinity DataKi:  2.20nM ΔG°:  -49.4kJ/mole IC50: 3.90nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM50123957((E)-5-(3-Benzenesulfonylamino-phenyl)-pent-2-en-4-...)copy SMILEScopy InChI
Affinity DataKi:  4.30nM ΔG°:  -47.8kJ/mole IC50: 7.5nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [60-420](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198120(TSA)copy SMILEScopy InChI
Affinity DataKi:  4.80nM ΔG°:  -47.5kJ/mole IC50: 7nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198122(HC toxin)copy SMILEScopy InChI
Affinity DataKi:  350nM ΔG°:  -36.8kJ/mole IC50: 600nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198123(Trifluoroketone)copy SMILEScopy InChI
Affinity DataKi:  800nM ΔG°:  -34.8kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [60-420](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  1.60E+3nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  50nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [440-798,S531A](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  170nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [84-835,H651V](Homo sapiens (Human))
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  3.00E+4nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [84-835,H255V](Homo sapiens (Human))
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  240nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [84-835](Homo sapiens (Human))
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  300nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed
TargetHistone deacetylase 6 [60-420,H82F,F202Y](Danio rerio)
University of Pennsylvania,

LigandPNGBDBM198125(fl-SAHA)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8KH1PubMed