Compile Data Set for Download or QSAR
Found 240 with Last Name = 'zaharevitz' and Initial = 'dw'
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50035468(4-(4-Hydroxy-9,10-dioxo-9,10-dihydro-anthracen-1-y...)copy SMILEScopy InChI
Affinity DataKi:  7.80E+3nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN36W8PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50035469(2-hydroxy-1-(2-hydroxy-1-phenylcarbonyloxyethyl)-3...)copy SMILEScopy InChI
Affinity DataKi:  1.29E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN36W8PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50035466(2-[1-[Bis-(2-hydroxy-ethyl)-amino]-meth-(Z)-yliden...)copy SMILEScopy InChI
Affinity DataKi:  1.61E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN36W8PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50035467(3-(4-Hydroxy-9,10-dioxo-9,10-dihydro-anthracen-1-y...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN36W8PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50035470(Acetic acid 2-((1S,2R,4aR,5S,8aR)-6-acetoxy-5-acet...)copy SMILEScopy InChI
Affinity DataKi:  3.77E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN36W8PubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7264(2,3-dimethoxy-9-nitropaullone | 4,5-dimethoxy-14-n...)copy SMILEScopy InChI
Affinity DataIC50: 13nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7265(4,5-dimethoxy-9-oxo-8,18-diazatetracyclo[9.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 18nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7264(2,3-dimethoxy-9-nitropaullone | 4,5-dimethoxy-14-n...)copy SMILEScopy InChI
Affinity DataIC50: 21nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universität Hamburg

Curated by ChEMBL
LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1W2RPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7267(14-chloro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12...)copy SMILEScopy InChI
Affinity DataIC50: 24nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7264(2,3-dimethoxy-9-nitropaullone | 4,5-dimethoxy-14-n...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7268(14-(trifluoromethyl)-8,18-diazatetracyclo[9.7.0.0^...)copy SMILEScopy InChI
Affinity DataIC50: 30nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7269(3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-ind...)copy SMILEScopy InChI
Affinity DataIC50: 33nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7269(3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-ind...)copy SMILEScopy InChI
Affinity DataIC50: 33nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universität Hamburg

Curated by ChEMBL
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1W2RPubMedDrugBank
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)copy SMILEScopy InChI
Affinity DataIC50: 40nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMedDrugBank
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7265(4,5-dimethoxy-9-oxo-8,18-diazatetracyclo[9.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 44nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7269(3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-ind...)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
LigandPNGBDBM7269(3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-ind...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B from Starfish oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60N98PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7280(2-Bromo-9-Nitropaullone | 4-bromo-14-nitro-8,18-di...)copy SMILEScopy InChI
Affinity DataIC50: 53nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7265(4,5-dimethoxy-9-oxo-8,18-diazatetracyclo[9.7.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7270(2,3-dimethoxy-9-trifluoromethylpaullone | 4,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 75nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7271(9-bromo-12-methyloxycarbonylmethylpaullone | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 75nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7272(14-fluoro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12...)copy SMILEScopy InChI
Affinity DataIC50: 80nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7273(14-bromo-4,5-dimethoxy-8,18-diazatetracyclo[9.7.0....)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
CNRS

LigandPNGBDBM7280(2-Bromo-9-Nitropaullone | 4-bromo-14-nitro-8,18-di...)copy SMILEScopy InChI
Affinity DataIC50: 120nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7274(14-bromo-4,5-dihydroxy-8,18-diazatetracyclo[9.7.0....)copy SMILEScopy InChI
Affinity DataIC50: 120nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7275(14-methyl-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12...)copy SMILEScopy InChI
Affinity DataIC50: 130nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7276(10-bromopaullone | 15-bromo-8,18-diazatetracyclo[9...)copy SMILEScopy InChI
Affinity DataIC50: 140nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-FCRDC

Curated by ChEMBL
LigandPNGBDBM50050632(8-ETHYL-6-METHOXY-3-METHYL-8H-1,3A,7,8,9-PENTAAZA-...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6XJ4PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universität Hamburg

Curated by ChEMBL
LigandPNGBDBM7273(14-bromo-4,5-dimethoxy-8,18-diazatetracyclo[9.7.0....)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1W2RPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7280(2-Bromo-9-Nitropaullone | 4-bromo-14-nitro-8,18-di...)copy SMILEScopy InChI
Affinity DataIC50: 200nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7279(2-(3-hydroxy-1-propinyl)-9-trifluoromethylpaullone...)copy SMILEScopy InChI
Affinity DataIC50: 200nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7278(11-chloropaullone | 16-chloro-8,18-diazatetracyclo...)copy SMILEScopy InChI
Affinity DataIC50: 200nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7277(2-Bromopaullone | 4-bromo-8,18-diazatetracyclo[9.7...)copy SMILEScopy InChI
Affinity DataIC50: 200nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7273(14-bromo-4,5-dimethoxy-8,18-diazatetracyclo[9.7.0....)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universität Hamburg

Curated by ChEMBL
LigandPNGBDBM7298(2-bromo-9-trifluoromethylpaullone | 4-bromo-14-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1W2RPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7298(2-bromo-9-trifluoromethylpaullone | 4-bromo-14-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 240nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7281(2-iodopaullone | 4-iodo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 250nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7284((2E)-3-[9-oxo-14-(trifluoromethyl)-8,18-diazatetra...)copy SMILEScopy InChI
Affinity DataIC50: 270nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
LigandPNGBDBM7284((2E)-3-[9-oxo-14-(trifluoromethyl)-8,18-diazatetra...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B from Starfish oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60N98PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universität Hamburg

Curated by ChEMBL
LigandPNGBDBM7270(2,3-dimethoxy-9-trifluoromethylpaullone | 4,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1W2RPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7270(2,3-dimethoxy-9-trifluoromethylpaullone | 4,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
CNRS

LigandPNGBDBM7279(2-(3-hydroxy-1-propinyl)-9-trifluoromethylpaullone...)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
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