Compile Data Set for Download or QSAR
Found 130 with Last Name = 'dagostino' and Initial = 'e'
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389112(CHEMBL2064556)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)copy SMILEScopy InChI
Affinity DataKi:  6nM ΔG°:  -45.4kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50314714((R)-N-(1-(3-fluorophenyl)-3-hydroxypropan-2-yl)ben...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
LigandPNGBDBM34011(3-fluorophenylalanine derivative, 21a)copy SMILEScopy InChI
Affinity DataKi:  8nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056217(CHEMBL3353369)copy SMILES
Affinity DataKi:  12nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389120(CHEMBL2064565)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34013(3-methylphenylalanine derivative, 22a)copy SMILEScopy InChI
Affinity DataKi:  32nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM34014(3-methylphenylalanine derivative, 22b)copy SMILEScopy InChI
Affinity DataKi:  57nM ΔG°:  -40.0kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389109(CHEMBL2064557)copy SMILEScopy InChI
Affinity DataKi:  64nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389119(CHEMBL2064564)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056216(CHEMBL3353368)copy SMILES
Affinity DataKi:  75nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056208(CHEMBL3322220)copy SMILES
Affinity DataKi:  76nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34015(2,3-difluorophenylalanine derivative, 23a)copy SMILEScopy InChI
Affinity DataKi:  78nM ΔG°:  -39.2kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056214(CHEMBL3322219)copy SMILES
Affinity DataKi:  80nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34016(2,3-difluorophenylalanine derivative, 23b)copy SMILEScopy InChI
Affinity DataKi:  89nM ΔG°:  -38.9kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389118(CHEMBL2064563)copy SMILEScopy InChI
Affinity DataKi:  98nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34009(naphthalene carboxamide, 18a)copy SMILEScopy InChI
Affinity DataKi:  100nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056211(CHEMBL3322225)copy SMILES
Affinity DataKi:  138nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056204(CHEMBL3322215)copy SMILES
Affinity DataKi:  173nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50314715((R)-N-(1-hydroxy-3-phenylpropan-2-yl)benzo[b]thiop...)copy SMILEScopy InChI
Affinity DataKi:  179nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
LigandPNGBDBM34010(benzothiophene carboxamide, 18b)copy SMILEScopy InChI
Affinity DataKi:  179nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
LigandPNGBDBM50056205(CHEMBL3322216)copy SMILES
Affinity DataKi:  189nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056219(CHEMBL3322230)copy SMILES
Affinity DataKi:  196nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389115(CHEMBL2064560)copy SMILEScopy InChI
Affinity DataKi:  207nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056220(CHEMBL3322295)copy SMILES
Affinity DataKi:  320nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056215(CHEMBL3353367)copy SMILES
Affinity DataKi:  400nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056207(CHEMBL3322218)copy SMILES
Affinity DataKi:  424nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389114(CHEMBL2064559)copy SMILEScopy InChI
Affinity DataKi:  512nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34008(amide, 17c)copy SMILEScopy InChI
Affinity DataKi:  525nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056203(CHEMBL3322296)copy SMILES
Affinity DataKi:  580nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056206(CHEMBL3322217)copy SMILES
Affinity DataKi:  780nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34005(pipecolate deriv., 12b)copy SMILEScopy InChI
Affinity DataKi:  800nM ΔG°:  -33.6kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50314706((R)-2-(2-naphthamido)-5-(3-fluorophenyl)pent-4-eno...)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
LigandPNGBDBM50056210(CHEMBL3322222)copy SMILES
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)copy SMILEScopy InChI
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056218(CHEMBL3322229)copy SMILES
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34003(pipecolate deriv., 11)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nM ΔG°:  -31.8kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50314682((R)-2-(2-naphthamido)-3-(3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50314705((2R,4E)-2-[(naphthalen-2-ylcarbonyl)amino]-5-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM50314701((R)-2-(2-naphthamido)-5-(3-fluorophenyl)pent-4-yno...)copy SMILEScopy InChI
Affinity DataKi:  1.87E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
LigandPNGBDBM50056212(CHEMBL3322224)copy SMILES
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50314685((R)-3-(2-naphthamido)-4-(3-chlorophenyl)butanoic a...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50314708((R)-2-(2-naphthamido)-5-cyclohexenylpent-4-enoic a...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4BPWPubMed
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