Compile Data Set for Download or QSAR
Found 93 with Last Name = 'greenberg' and Initial = 'e'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataKi:  21nM ΔG°:  -43.4kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22450(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)copy SMILEScopy InChI
Affinity DataKi:  28nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataKi:  48nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22450(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)copy SMILEScopy InChI
Affinity DataKi:  88nM ΔG°:  -39.9kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataKi:  142nM ΔG°:  -38.7kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataKi:  995nM ΔG°:  -33.9kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nM ΔG°:  -32.2kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22450(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)copy SMILEScopy InChI
Affinity DataKi:  6.10E+3nM ΔG°:  -29.5kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nM ΔG°:  -29.4kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZG2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM25142((3S,6S,9S,15aR)-9-[(2R)-butan-2-yl]-6-[(1-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50342750(CHEMBL1771484 | N,8-dihydroxy-8-(2-(4-(prop-2-ynyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC835MPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342750(CHEMBL1771484 | N,8-dihydroxy-8-(2-(4-(prop-2-ynyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC835MPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29602(benzylidenehydrazine derivative, 19)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29593(benzylidenehydrazine derivative, 10)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29595(benzylidenehydrazine derivative, 12)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50342752(3-(2-(3-(((R)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC835MPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMedDrugBank
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50342751(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC835MPubMed
TargetQuorum-sensing transcriptional repressor QscR(Pseudomonas aeruginosa)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50373105(CHEMBL259441)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assessed as inhibition of dodecanoyl homoserine lactone induced prod...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3TM8PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11N4PubMedDrugBank
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC835MPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29603(benzylidenehydrazine derivative, 20)copy SMILEScopy InChI
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29599(benzylidenehydrazine derivative, 16)copy SMILEScopy InChI
Affinity DataIC50: 37nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29596(benzylidenehydrazine derivative, 13)copy SMILEScopy InChI
Affinity DataIC50: 37nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29597(benzylidenehydrazine derivative, 14)copy SMILEScopy InChI
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29594(benzylidenehydrazine derivative, 11)copy SMILEScopy InChI
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29607(benzylidenehydrazine derivative, 24)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29598(benzylidenehydrazine derivative, 15)copy SMILEScopy InChI
Affinity DataIC50: 49nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50342749(3-(2-benzylidenehydrazinecarbonyl)-N-hydroxybenzam...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC835MPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29606(benzylidenehydrazine derivative, 23)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29600(benzylidenehydrazine derivative, 17)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29591(benzylidenehydrazine derivative, 8)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29605(benzylidenehydrazine derivative, 22)copy SMILEScopy InChI
Affinity DataIC50: 89nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Harvard Medical School

LigandPNGBDBM29601(benzylidenehydrazine derivative, 18)copy SMILEScopy InChI
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:Recombinant pfHDAC-1 was assayed with substrate in the presence of test compound. The substrate concentration was kept constant at 125 uM while the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4FRDPubMed
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