Compile Data Set for Download or QSAR
Found 177 with Last Name = 'knauth' and Initial = 'e'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322393((S)-N-((3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24923(5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-b...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24922(5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137175(2-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137175(2-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137190((1H-Indol-5-yl)-(2-thiophen-2-yl-thieno[3,2-b]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322395((S)-N-((3-amino-1-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137195(CHEMBL312753 | {4-[4-(1H-Indol-5-ylamino)-thieno[3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137199(1-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137193(CHEMBL79215 | N*4*-(1H-Indol-5-yl)-N*6*-(2-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322394((S)-N-((3-amino-1-(5-chloro-7H-pyrrolo[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322401((S)-N-((3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322397((S)-N-((3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM24855(4-{1,2-dihydrospiro[indole-3,4'-piperidine]}-7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137194(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137208(1-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137177(CHEMBL418909 | N-(2-{4-[7-(1H-Indol-5-ylamino)-thi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM24855(4-{1,2-dihydrospiro[indole-3,4'-piperidine]}-7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:A fluorescence polarization IMAP type assay is used. After a 90 min incubation of reaction mixtures containing enzyme, substrate, and inhibitor, IMAP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043QCPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322402((S)-N-((3-amino-1-(5-chloro-7H-pyrrolo[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24899(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylca...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322403((S)-N-((3-amino-1-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137206((2-Methyl-1H-indol-5-yl)-(2-{4-[(2-pyridin-1-yl-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137203((1H-Indol-5-yl)-(2-{4-[(2-pyridin-1-yl-ethylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137202(2-(Methyl-{4-[7-(2-methyl-1H-indol-5-ylamino)-thie...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137198(2-({4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM24848(5-fluoro-1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1,2-d...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:A fluorescence polarization IMAP type assay is used. After a 90 min incubation of reaction mixtures containing enzyme, substrate, and inhibitor, IMAP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043QCPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322398((S)-N-((3-amino-1-(5-chloro-7H-pyrrolo[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137210(3-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137192(2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50322388(5-chloro-4-(2,8-diazaspiro[4.5]decan-2-yl)-7H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of AKT1 after 90 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X580CPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137200(CHEMBL78018 | [6-(4-Aminomethyl-phenyl)-thieno[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24901(3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137198(2-({4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137184(2-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137192(2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137205(CHEMBL80809 | N-(2-{4-[4-(1H-Indol-5-ylamino)-thie...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM24853(1-{5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1,2-d...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMpH: 7.5 T: 2°CAssay Description:A fluorescence polarization IMAP type assay is used. After a 90 min incubation of reaction mixtures containing enzyme, substrate, and inhibitor, IMAP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043QCPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM24847(5-chloro-1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1,2-d...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMpH: 7.5 T: 2°CAssay Description:A fluorescence polarization IMAP type assay is used. After a 90 min incubation of reaction mixtures containing enzyme, substrate, and inhibitor, IMAP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043QCPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137181((2-Methyl-1H-indol-5-yl)-[2-(4-morpholin-4-ylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137172(3-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137179(2-(2-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137187((1H-Indol-5-yl)-[2-(4-morpholin-4-ylmethyl-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137201(CHEMBL77782 | {6-[4-(2-Dimethylamino-ethyl)-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137183((3-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
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