Compile Data Set for Download or QSAR
Found 7 with Last Name = 'macia' and Initial = 'e'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Frederick National Laboratory for Cancer Research

Curated by ChEMBL
LigandPNGBDBM27543(4-{[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]meth...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917DVPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Frederick National Laboratory for Cancer Research

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Frederick National Laboratory for Cancer Research

Curated by ChEMBL
LigandPNGBDBM27542(4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917DVPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Frederick National Laboratory for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50007192(CHEMBL3237591)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins measured without activation by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917DVPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Frederick National Laboratory for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50007191(CHEMBL3237590)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins measured without activation by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917DVPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50324673(CHEMBL1222039 | Secramine B)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of GEF-independent nucleotide exchange activity of prenylated Cdc42 after 3 mins in presence of 4 mM Mg2+ chelator EDTAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60BRPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50324672(CHEMBL1222038 | Secramine A)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of GEF-independent nucleotide exchange activity of prenylated Cdc42 after 3 mins in presence of 4 mM Mg2+ chelator EDTAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60BRPubMed