Compile Data Set for Download or QSAR
Found 53 with Last Name = 'ohlstein' and Initial = 'e'
TargetEndothelin-1 receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85335(SB 234551 | SB-234551)copy SMILEScopy InChI
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40SSKPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50041617((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40SSKPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50061077((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40SSKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50059133(CHEMBL50106 | SB-223245 | {(S)-7-[(1H-Benzoimidazo...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072516(CHEMBL419374 | {(S)-4-(3,3-Dimethyl-butyl)-7-[(1H-...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072504(CHEMBL321648 | [(S)-7-[(1H-Imidazo[4,5-b]pyridin-2...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072509(CHEMBL107927 | {(S)-7-[(1H-Imidazo[4,5-b]pyridin-2...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072507(CHEMBL418818 | {(S)-4-Methyl-7-[methyl-(5-methyl-1...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072505(CHEMBL110520 | {(S)-7-[(1H-Imidazo[4,5-b]pyridin-2...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014978(1-(3,5-Difluoro-4-hydroxy-benzyl)-1,3-dihydro-imid...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3K55PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072513(CHEMBL105982 | {(S)-7-[Methyl-(5-methyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072517(CHEMBL320939 | {(S)-4-Benzyl-7-[methyl-(5-methyl-1...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072506(CHEMBL110506 | {(S)-7-[(5H-Imidazo[4,5-c]pyridazin...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50041617((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)copy SMILEScopy InChI
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40SSKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072510(CHEMBL419013 | {(S)-4-Methyl-7-[methyl-(7H-purin-8...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)copy SMILEScopy InChI
Affinity DataKi:  41nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3K55PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072515(CHEMBL110180 | {(S)-4-Methyl-7-[(5-methyl-1H-imida...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072512(CHEMBL108148 | {(S)-4-(2-Methoxy-ethyl)-7-[(5-meth...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014968(1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thion...)copy SMILEScopy InChI
Affinity DataKi:  55nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3K55PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072514(CHEMBL177255 | {(S)-4-Benzyl-7-[(5-methyl-1H-imida...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072511(CHEMBL105871 | {(S)-7-[(5-Methyl-1H-imidazo[4,5-b]...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50061101(4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...)copy SMILEScopy InChI
Affinity DataKi:  134nMMore data for this Ligand-Target Pair
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)copy SMILEScopy InChI
Affinity DataKi:  149nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3K55PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50061077((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy...)copy SMILEScopy InChI
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40SSKPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM85335(SB 234551 | SB-234551)copy SMILEScopy InChI
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40SSKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072508(CHEMBL110395 | {(S)-7-[(5,7-Dimethyl-1H-imidazo[4,...)copy SMILEScopy InChI
Affinity DataKi:  710nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85994PubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50023370(2-Thiophen-2-yl-allylamine | CHEMBL110604)copy SMILEScopy InChI
Affinity DataKi:  3.50E+4nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972KPPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50017834(4-(1-Aminomethyl-prop-2-ynyl)-phenol | CHEMBL16312...)copy SMILEScopy InChI
Affinity DataKi:  5.70E+4nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972KPPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50017834(4-(1-Aminomethyl-prop-2-ynyl)-phenol | CHEMBL16312...)copy SMILEScopy InChI
Affinity DataKi:  5.70E+4nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972KPPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50017827(4-(1-Aminomethyl-vinyl)-phenol | CHEMBL330118)copy SMILEScopy InChI
Affinity DataKi:  5.20E+5nMpH: 5.0Assay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]; Apparent values at pH 5.0, 0.24 mM O2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972KPPubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50023371(4-Cyclopropylmethyl-phenol | CHEMBL162030)copy SMILEScopy InChI
Affinity DataKi:  1.20E+6nMAssay Description:KI value was determined from plots of 1/kinact(observed) vs 1/[inhibitor]More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972KPPubMed
LigandPNGBDBM50282363(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
LigandPNGBDBM50048078(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282362(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the absence of BSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
LigandPNGBDBM50011975(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRFDrugBank
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284297(4-(2-Butyl-5-{[(R)-1-carboxy-2-(1H-indol-3-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Tested for inhibition of Angiotensin II specific binding to Angiotensin II receptor, type 1 in the recombinant human AT-1 receptor expressed in LhAT-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0TF6
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the presence of 0.25% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRFDrugBank
LigandPNGBDBM50282362(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282362(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the presence of 0.25% BSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
LigandPNGBDBM50048076(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284298(4-(2-Butyl-5-{[(S)-1-carboxy-2-(1H-indol-3-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 48.3nMAssay Description:Tested for inhibition of Angiotensin II specific binding to Angiotensin II receptor, type 1 in the recombinant human AT-1 receptor expressed in LhAT-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0TF6
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284295(4-{2-Butyl-5-[(carboxymethyl-amino)-methyl]-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 298nMAssay Description:Tested for inhibition of Angiotensin II specific binding to Angiotensin II receptor, type 1 in the recombinant human AT-1 receptor expressed in LhAT-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0TF6
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50048069((E)-3-(3-Benzyl-2-butyl-3H-imidazol-4-yl)-2-thioph...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Tested for binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z0MPubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 1.1-1.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z0MPubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014968(1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thion...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 1.3-4.6More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z0MPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003266((E)-3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 4.53E+3nMAssay Description:Tested for binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MRF
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value range from 8.9-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z0MPubMed
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