Compile Data Set for Download or QSAR
Found 40 with Last Name = 'rosethorne' and Initial = 'e'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421329(CHEMBL2088201)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421329(CHEMBL2088201)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMedDrugBank
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421327(CHEMBL2088199)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421325(CHEMBL2088197)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421330(CHEMBL2088202)copy SMILEScopy InChI
Affinity DataKi:  77nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421330(CHEMBL2088202)copy SMILEScopy InChI
Affinity DataKi:  133nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421328(CHEMBL2088200)copy SMILEScopy InChI
Affinity DataKi:  175nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421325(CHEMBL2088197)copy SMILEScopy InChI
Affinity DataKi:  183nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421324(CHEMBL2088196)copy SMILEScopy InChI
Affinity DataKi:  227nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421327(CHEMBL2088199)copy SMILEScopy InChI
Affinity DataKi:  259nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421326(CHEMBL2088198)copy SMILEScopy InChI
Affinity DataKi:  261nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421324(CHEMBL2088196)copy SMILEScopy InChI
Affinity DataKi:  382nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421328(CHEMBL2088200)copy SMILEScopy InChI
Affinity DataKi:  421nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421326(CHEMBL2088198)copy SMILEScopy InChI
Affinity DataKi:  478nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421323(CHEMBL2088195)copy SMILEScopy InChI
Affinity DataKi:  515nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataKi:  3.92E+3nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421323(CHEMBL2088195)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421325(CHEMBL2088197)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Agonist activity at beta2-adrenoceptor in guinea-pig tracheal-strip assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355897(CHEMBL1910163)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355899(CHEMBL1910165)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355898(CHEMBL1910164)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421326(CHEMBL2088198)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Agonist activity at beta2-adrenoceptor in guinea-pig tracheal-strip assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355893(CHEMBL1910159)copy SMILEScopy InChI
Affinity DataIC50: 261nMAssay Description:Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR1 expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355894(CHEMBL1910160)copy SMILEScopy InChI
Affinity DataIC50: 387nMAssay Description:Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR1 expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355895(CHEMBL1910161)copy SMILEScopy InChI
Affinity DataIC50: 925nMAssay Description:Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR2 expressed in CHO ducX#98 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355895(CHEMBL1910161)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355901(CHEMBL1910166)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-MIP-1- alpha from CCR5 expressed in CHO K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355900(CHEMBL1910167)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+3nMAssay Description:Displacement of [125I]-eotaxin from CCR3 expressed in RBL-2H3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355902(CHEMBL1910168)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]-MIP-1- alpha from CCR5 expressed in CHO K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355896(CHEMBL1910162)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:Displacement of [125I]-MIP-1alpha 125I]-MCP1 from CCR2 expressed in CHO ducX#98 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50355900(CHEMBL1910167)copy SMILEScopy InChI
Affinity DataIC50: 2.85E+3nMAssay Description:Displacement of [125I]-MIP-1- alpha from CCR5 expressed in CHO K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VTXPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at beta2-adrenoceptor in human bronchial smooth-muscle cell by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMedDrugBank
TargetD(2) dopamine receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421326(CHEMBL2088198)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase in GTPgamma35S binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50128690(4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfon...)copy SMILEScopy InChI
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase in GTPgamma35S binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase in GTPgamma35S binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421329(CHEMBL2088201)copy SMILEScopy InChI
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at beta2-adrenoceptor in human bronchial smooth-muscle cell by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50421329(CHEMBL2088201)copy SMILEScopy InChI
Affinity DataKd:  0.260nMAssay Description:Kinetic binding affinity to human beta2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed