Compile Data Set for Download or QSAR
Found 42 with Last Name = 'viayna gaza' and Initial = 'e'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202364(US9238626, (-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202362(US9238626, (+/-)-(Ia) HCl)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202366(US9238626, (+/-)-(Ic) HCl)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202364(US9238626, (-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 13.6nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202367(US9238626, (+/-)-(Id) HCl)copy SMILEScopy InChI
Affinity DataIC50: 16.3nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202367(US9238626, (+/-)-(Id) HCl)copy SMILEScopy InChI
Affinity DataIC50: 17.4nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202368(US9238626, (+/-)-(Ie) HCl)copy SMILEScopy InChI
Affinity DataIC50: 18.2nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 32.6nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202366(US9238626, (+/-)-(Ic) HCl)copy SMILEScopy InChI
Affinity DataIC50: 46.7nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202368(US9238626, (+/-)-(Ie) HCl)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202364(US9238626, (-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 80nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202365(US9238626, (+)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 80nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202362(US9238626, (+/-)-(Ia) HCl)copy SMILEScopy InChI
Affinity DataIC50: 88.6nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202365(US9238626, (+)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 98.9nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 120nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 181nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 222nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202365(US9238626, (+)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 265nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202362(US9238626, (+/-)-(Ia) HCl)copy SMILEScopy InChI
Affinity DataIC50: 350nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 373nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202368(US9238626, (+/-)-(Ie) HCl)copy SMILEScopy InChI
Affinity DataIC50: 510nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202364(US9238626, (-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 513nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 620nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 637nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202367(US9238626, (+/-)-(Id) HCl)copy SMILEScopy InChI
Affinity DataIC50: 645nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202362(US9238626, (+/-)-(Ia) HCl)copy SMILEScopy InChI
Affinity DataIC50: 980nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202366(US9238626, (+/-)-(Ic) HCl)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202366(US9238626, (+/-)-(Ic) HCl)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+3nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202367(US9238626, (+/-)-(Id) HCl)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202368(US9238626, (+/-)-(Ie) HCl)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+3nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM202365(US9238626, (+)-(Ib) HCl)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+3nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:β-Secretase (BACE-1, Sigma) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (methoxycoumarin-Ser-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity of compounds (Ia)-(Ie) and (-)-(Ib) and (+)-(Ib) was evaluated spectrophotometrically at 25° C. by the method of Ellma...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent
TargetCholinesterase(Homo sapiens (Human))
UNIVERSITAT DE BARCELONA; PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

US Patent
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T152FZUS Patent