Compile Data Set for Download or QSAR
Found 86 with Last Name = 'watts' and Initial = 'e'
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200152(CHEMBL219427 | quinolin-3-ylmethyl (S)-1-(((S)-3-b...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200155((S)-quinolin-3-ylmethyl 1-((3-bromo-4,5-dihydroiso...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200156((S)-quinolin-3-ylmethyl 2-((((S)-3-bromo-4,5-dihyd...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200154(CHEMBL220137 | [1-[(3-bromo-4,5-dihydroisoxazol-5-...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200145(CHEMBL375426 | quinolin-3-ylmethyl 1-((3-bromo-4,5...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200149(CHEMBL219013 | [1-[(3-bromo-4,5-dihydroisoxazol-5-...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200147(CHEMBL410077 | [1-[(3-bromo-4,5-dihydroisoxazol-5-...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200151(CHEMBL374790 | quinolin-3-ylmethyl (S)-1-(((S)-3-b...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200153(CHEMBL384892 | quinolin-3-ylmethyl 1-((3-bromo-4,5...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200159((S)-quinolin-3-ylmethyl 1-((3-bromo-4,5-dihydroiso...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200146(CHEMBL216391 | quinolin-3-ylmethyl 1-((3-bromo-4,5...)copy SMILEScopy InChI
Affinity DataKi:  5.10E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200157((S)-quinolin-3-ylmethyl 2-(((3-bromo-4,5-dihydrois...)copy SMILEScopy InChI
Affinity DataKi:  6.20E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200148(CHEMBL375595 | benzyl (S)-1-(((S)-3-bromo-4,5-dihy...)copy SMILEScopy InChI
Affinity DataKi:  6.80E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200158(CHEMBL374887 | [1-[(3-bromo-4,5-dihydroisoxazol-5-...)copy SMILEScopy InChI
Affinity DataKi:  9.90E+4nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50200150(2-[(3-bromo-4,5-dihydroisoxazol-5-ylmethyl)carbamo...)copy SMILEScopy InChI
Affinity DataKi:  1.38E+5nMAssay Description:Inhibition of human recombinant TG2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280771PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50573631(CHEMBL4873767)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
LigandPNGBDBM50573631(CHEMBL4873767)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of RIP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
LigandPNGBDBM50573633(CHEMBL4869572)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of RIP2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526301(CHEMBL4456099)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526302(CHEMBL4464826)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50573632(CHEMBL4876135)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
LigandPNGBDBM50573632(CHEMBL4876135)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of RIP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526296(CHEMBL4449858)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526309(CHEMBL4543331)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526309(CHEMBL4543331)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50436850(CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of ALK F1174L mutant auto-phosphorylation in human Kelly cells after 3 hrs by MSD assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50573631(CHEMBL4873767)copy SMILES
Affinity DataIC50: 79nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526303(CHEMBL4457809)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526295(CHEMBL4469087)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50573631(CHEMBL4873767)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21PVPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526300(CHEMBL4469756)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526296(CHEMBL4449858)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526305(CHEMBL4557730)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526297(CHEMBL4448214)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526307(CHEMBL4519103)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526296(CHEMBL4449858)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of full-length C-terminal NanoLuc-tagged BRD4 BD1 (unknown origin) expressed in human HEK293 cells after 2 hrs by NanoBRET target engageme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526304(CHEMBL4451065)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526301(CHEMBL4456099)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526295(CHEMBL4469087)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of full-length C-terminal NanoLuc-tagged BRD4 BD1 (unknown origin) expressed in human HEK293 cells after 2 hrs by NanoBRET target engageme...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526309(CHEMBL4543331)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of full-length C-terminal NanoLuc-tagged BRD4 BD1 (unknown origin) expressed in human HEK293 cells after 2 hrs by NanoBRET target engageme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526299(CHEMBL4454885)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526294(CHEMBL4588843)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526308(CHEMBL4549308)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526302(CHEMBL4464826)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526303(CHEMBL4457809)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526296(CHEMBL4449858)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of full-length C-terminal NanoLuc-tagged ALK (unknown origin) expressed in human HEK293 cells after 2 hrs by NanoBRET target engagement as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TBZPubMed
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