Compile Data Set for Download or QSAR
Found 110 with Last Name = 'knauth' and Initial = 'ea'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137175(2-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137175(2-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137190((1H-Indol-5-yl)-(2-thiophen-2-yl-thieno[3,2-b]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24922(5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24923(5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-b...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137195(CHEMBL312753 | {4-[4-(1H-Indol-5-ylamino)-thieno[3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137193(CHEMBL79215 | N*4*-(1H-Indol-5-yl)-N*6*-(2-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137199(1-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137177(CHEMBL418909 | N-(2-{4-[7-(1H-Indol-5-ylamino)-thi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137208(1-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137194(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24899(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylca...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137206((2-Methyl-1H-indol-5-yl)-(2-{4-[(2-pyridin-1-yl-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137203((1H-Indol-5-yl)-(2-{4-[(2-pyridin-1-yl-ethylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137202(2-(Methyl-{4-[7-(2-methyl-1H-indol-5-ylamino)-thie...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137198(2-({4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137192(2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24901(3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137210(3-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137192(2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137184(2-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137205(CHEMBL80809 | N-(2-{4-[4-(1H-Indol-5-ylamino)-thie...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137200(CHEMBL78018 | [6-(4-Aminomethyl-phenyl)-thieno[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137198(2-({4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137181((2-Methyl-1H-indol-5-yl)-[2-(4-morpholin-4-ylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137173(CHEMBL312818 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137172(3-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137179(2-(2-{4-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137187((1H-Indol-5-yl)-[2-(4-morpholin-4-ylmethyl-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137201(CHEMBL77782 | {6-[4-(2-Dimethylamino-ethyl)-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137183((3-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137205(CHEMBL80809 | N-(2-{4-[4-(1H-Indol-5-ylamino)-thie...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137194(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137203((1H-Indol-5-yl)-(2-{4-[(2-pyridin-1-yl-ethylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24898(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(methylcar...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137208(1-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24919(3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137171(CHEMBL81712 | [4-(1H-Indol-5-ylamino)-thieno[3,2-d...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24900(3-{[1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylc...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137210(3-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24918(5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24903(3-{[1-(4-chlorophenyl)-2-methylpropyl]sulfanyl}-5-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137199(1-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50137200(CHEMBL78018 | [6-(4-Aminomethyl-phenyl)-thieno[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8KFTPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24910(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
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