Compile Data Set for Download or QSAR
Found 225 with Last Name = 'muth' and Initial = 'ea'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  0.760nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367721(CHEMBL1202512)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367437(CHEMBL1743956)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367438(CHEMBL1743957)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367726(CHEMBL1202507)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367719(CHEMBL1202513)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367735(CHEMBL1204093)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound; value may ra...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetNorepinephrine transporter(RAT)
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataKi:  3.14nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367417(CHEMBL1743943)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]spiperone as the radioligand in rat cortical tissue; value may range from 2.4 to 5.3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35SNVPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compoundMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367419(CHEMBL1743958)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367733(CHEMBL1202527)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367736(CHEMBL1202530)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367433(CHEMBL1743945)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367417(CHEMBL1743943)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50020115(4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4-az...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35SNVPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]-Spiperone as the radioligand in rat cortical tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367731(CHEMBL1202506)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367432(CHEMBL1743937)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367723(CHEMBL1202494)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50020142(4-{4-[4-(3-chlorophenyl)hexahydro-1-pyrazinyl]buty...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367725(CHEMBL1202520)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367726(CHEMBL1202507)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat brain limbic tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367734(CHEMBL1202523)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367729(CHEMBL1204094)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367425(CHEMBL1743955)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50020126(4-{4-[4-(3-chlorophenyl)hexahydro-1-pyrazinyl]buty...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367732(CHEMBL1202493)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wyeth Laboratories, Inc.

Curated by PDSP Ki Database
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J69CPPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367419(CHEMBL1743958)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]spiperone as the radioligand in rat cortical tissue; value may range from 6 to 75More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367728(CHEMBL1202515)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367422(CHEMBL1743935)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367730(CHEMBL1202508)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50020145(4-{4-[4-(3-chloro-2-pyrazinyl)hexahydro-1-pyraziny...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound; value may ra...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367435(CHEMBL1743938)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]-Spiperone as the radioligand in rat cortical tissue; value may range from 12 to 66More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:In vitro binding affinity for dopamine receptor D2 of rat nucleus accumbens labeled with [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35SNVPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]-Spiperone as the radioligand in rat limbic system at 1 uM concentration of compoundMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VG2PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50020121(4-[4-(3'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazin...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32Z4PubMed
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