Compile Data Set for Download or QSAR
Found 551 with Last Name = 'spieser' and Initial = 'ea'
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213662(US9278981, 254)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213677(US9278981, 269)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213659(US9278981, 251)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213682(US9278981, 274)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213656(US9278981, 248)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213655(US9278981, 247)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213613(US9278981, 205)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213603(US9278981, 195)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213581(US9278981, 173)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213579(US9278981, 171)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213578(US9278981, 170)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213559(US9278981, 151)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213496(US9278981, 88)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213677(US9278981, 269)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213673(US9278981, 265)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213671(US9278981, 263)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213667(US9278981, 259)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213595(US9278981, 187)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213589(US9278981, 181)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213583(US9278981, 175)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213596(US9278981, 188)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213593(US9278981, 185)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213594(US9278981, 186)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213699(US9278981, 291)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213448(US9278981, 40)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213631(US9278981, 223)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213486(US9278981, 78)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213516(US9278981, 108)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213688(US9278981, 280)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213497(US9278981, 89)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213580(US9278981, 172)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213707(US9278981, 299)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213585(US9278981, 177)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213676(US9278981, 268)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213586(US9278981, 178)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213682(US9278981, 274)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213548(US9278981, 140)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213588(US9278981, 180)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213478(US9278981, 70)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213474(US9278981, 66)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213461(US9278981, 53)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213601(US9278981, 193)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213606(US9278981, 198)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213625(US9278981, 217)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213664(US9278981, 256)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213525(US9278981, 117)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213598(US9278981, 190)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213614(US9278981, 206)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213617(US9278981, 209)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM213651(US9278981, 243)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HRDUS Patent
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