Compile Data Set for Download or QSAR
Found 66 with Last Name = 'haura' and Initial = 'eb'
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50580856(CHEMBL5074481)copy SMILES
Affinity DataKi:  140nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50139763(CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-fused Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z6SPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50580855(CHEMBL1205233)copy SMILES
Affinity DataIC50: 4.30nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z6SPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209931(c-Rucaparib)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209930(c-Olaparib)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209933(c-Veliparib)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)copy SMILEScopy InChI
Affinity DataIC50: 11.7nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Binding affinity to Grb2-SH2 domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z6SPubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50072862(CHEMBL117807 | Phosphoric acid mono-[4-((S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of GST-fused human Grb2-SH2 domain expressed in Escherichia coli by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z6SPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209929(c-Niraparib)copy SMILEScopy InChI
Affinity DataIC50: 48.4nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382684(CHEMBL2023158 | US9409868, 24)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382685(CHEMBL2023156 | US9409868, 22)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50102025(4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAP...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50580856(CHEMBL5074481)copy SMILES
Affinity DataIC50: 740nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382687(CHEMBL2023152 | US9409868, 16)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382688(CHEMBL2023155 | US9409868, 19)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382689(CHEMBL2023153 | US9409868, 17)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382685(CHEMBL2023156 | US9409868, 22)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382690(CHEMBL2023160 | US9409868, 26)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382691(CHEMBL2023151 | US9409868, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382684(CHEMBL2023158 | US9409868, 24)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382689(CHEMBL2023153 | US9409868, 17)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382692(CHEMBL2023150)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382688(CHEMBL2023155 | US9409868, 19)copy SMILEScopy InChI
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382687(CHEMBL2023152 | US9409868, 16)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382693(CHEMBL2023159 | US9409868, 25)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382691(CHEMBL2023151 | US9409868, 15)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382692(CHEMBL2023150)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382690(CHEMBL2023160 | US9409868, 26)copy SMILEScopy InChI
Affinity DataIC50: 5.36E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50196697(1-benzyl-3-(1H-indazol-5-yl)urea | CHEMBL225282 | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382694(CHEMBL2023149 | US9409868, 13)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382695(CHEMBL2023157 | US9409868, 23)copy SMILEScopy InChI
Affinity DataIC50: 7.52E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50060523(CHEMBL118574 | Phosphoric acid mono-(4-{(S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 8.64E+3nMAssay Description:Inhibition of GST-fused human Grb2-SH2 domain expressed in Escherichia coli by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z6SPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382695(CHEMBL2023157 | US9409868, 23)copy SMILEScopy InChI
Affinity DataIC50: 9.07E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50196697(1-benzyl-3-(1H-indazol-5-yl)urea | CHEMBL225282 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetGDH/6PGL endoplasmic bifunctional protein(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:HEK293 H6PD-OE and HEK293 pellets were lysed and the lysate was quantified with the Bradford protein assay. Reaction mix containing galactose-6-phosp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2V0BPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382693(CHEMBL2023159 | US9409868, 25)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))TBA
LigandPNGBDBM50580857(CHEMBL5088383)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z6SPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382694(CHEMBL2023149 | US9409868, 13)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382696(CHEMBL2023161 | US9409868, 27)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382696(CHEMBL2023161 | US9409868, 27)copy SMILEScopy InChI
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382697(CHEMBL2023147 | US9409868, 10)copy SMILEScopy InChI
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50246684(CHEMBL503641 | N-(1H-indazol-5-yl)acetamide)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QH3PubMed
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