Compile Data Set for Download or QSAR
Found 522 with Last Name = 'bayle' and Initial = 'ed'
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50396023(CHEMBL2169919)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant DOT1L (1 to 416 residues) using chicken erythrocyte oligonucleosomes as substrate and [3H]-SAM incubated for 120 mins...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50396981(CHEMBL2171174)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Inhibition of recombinant human DOT1L (1 to 472 residues) preincubated for 10 mins prior addition of [3H]SAM measured after 30 mins by Beckman LS-650...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50443016(CHEMBL3087498)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M697HPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50144578(CHEMBL3760062)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28F9PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539233(CHEMBL4642625)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539213(CHEMBL4637176)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539211(CHEMBL4642915)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539244(CHEMBL4648963)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539246(CHEMBL4632439)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154387(CHEMBL3774528)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28F9PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539220(CHEMBL4646043)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539221(CHEMBL4637948)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539212(CHEMBL4648770)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50396980(CHEMBL2171169)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M697HPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601043(4-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-tria...)copy SMILES
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154387(CHEMBL3774528)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601048(2-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539243(CHEMBL4637227)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539214(CHEMBL4641132)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600981(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-(meth...)copy SMILES
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539222(CHEMBL4643862)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539223(CHEMBL4634865)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539248(CHEMBL4633059)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539234(CHEMBL4641550)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539216(CHEMBL4636343)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600982(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-ethox...)copy SMILES
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601045(4,5-dideuterio-1-[2,4-dichloro-3-(trifluoromethyl)...)copy SMILES
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)copy SMILES
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601001(5-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...)copy SMILES
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539210(CHEMBL4641545)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154370(CHEMBL1689356)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600981(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-(meth...)copy SMILES
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)copy SMILES
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539215(CHEMBL4647057)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)copy SMILES
Affinity DataIC50: 6.30nMMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)copy SMILES
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539247(CHEMBL4636894)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539209(CHEMBL4640648)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600986(N-(5-(2,4-dichloro-3-(trifluoromethyl)phenyl)-1,3,...)copy SMILES
Affinity DataIC50: 7.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601044(3,5-dichloro-2-(triazol-1-yl)-4-(trifluoromethyl)p...)copy SMILES
Affinity DataIC50: 7.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0SDZPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539203(CHEMBL4646342)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPeregrin(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human BRPF1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4DQ5PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600827(4-(3,4-bis(trifluoromethyl)phenyl)-1H-1,2,3-triazo...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))TBA
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28F9PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601044(3,5-dichloro-2-(triazol-1-yl)-4-(trifluoromethyl)p...)copy SMILES
Affinity DataIC50: 8.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539236(CHEMBL4632898)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPeregrin(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50249785(CHEMBL4069814)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human BRPF1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4DQ5PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539245(CHEMBL4632460)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
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