Compile Data Set for Download or QSAR
Found 349 with Last Name = 'meredith' and Initial = 'el'
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324297(4-(1-Piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50500363(CHEMBL3747481)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50500371(CHEMBL3746941)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324315(CHEMBL1214998 | Cyclohexyl-[4-(1-piperazin-1-yl[2,...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324315(CHEMBL1214998 | Cyclohexyl-[4-(1-piperazin-1-yl[2,...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270431(CHEMBL4076909)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50500370(CHEMBL3746273)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324306(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324347(CHEMBL1215153 | Isopropyl-[6-piperazin-1-yl-4-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324348(6-(piperazin-1-yl)-4-(4H-pyrazol-4-yl)-N-(tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324323(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324346(CHEMBL1215151 | Cyclohexyl-[6-piperazin-1-yl-4-(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50500377(CHEMBL3747084)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50453428(CHEMBL4205098)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length recombinant human NAMPT using N15-NAM as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324324(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324346(CHEMBL1215151 | Cyclohexyl-[6-piperazin-1-yl-4-(1H...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324327(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324324(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324326(4'-tert-Butylcarbamoyl-2''-isopropylamino-3,4,5,6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324325(6-Piperazin-1-yl-2'-(tetrahydropyran-4-ylamino)[2,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324314(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324298(CHEMBL1215712 | {4-[1-(4-Isobutylpiperazin-1-yl)[2...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324296(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324305(CHEMBL1214711 | N-(2-(pyrrolidin-1-yl)ethyl)-1-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324322(4-(2-cyclohexylaminopyridin-4-yl)-6-(piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270430(CHEMBL4077373)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270425(CHEMBL4080062)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444552(CHEMBL3099689)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270439(CHEMBL4104297)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444564(CHEMBL3099682)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324309(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324292(CHEMBL1215641 | Cyclohexyl-{4-[1-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324294(CHEMBL1215643 | Cyclohexyl-{4-[1-(4-cyclopropylmet...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324335(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84C2JPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324313(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444565(CHEMBL3099604)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270433(CHEMBL4086718)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324312(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
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