TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/cyclinE assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 5.35nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 8.02nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 8.12nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 16.5nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 22.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 23.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK1/cyclinB1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 60.2nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of CDK9/cyclinT assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK2/cyclinE assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 15(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of CDK9/cyclinT assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of CK1More data for this Ligand-Target Pair
TargetInsulin receptor-related protein(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IRRMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CDK1/cyclinB1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of CAMKKbetaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of CDK4/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CDK4/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of CDK6/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of CDK6/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 26.1nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 12.4nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 16.8nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 50.1nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 16.7nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 12.6nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 29.4nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
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