Compile Data Set for Download or QSAR
Found 35 with Last Name = 'pettipher' and Initial = 'er'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102438(US8536158, B)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102440(US8536158, D)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102436(US8536158, 2)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102435(US8536158, 1)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102437(US8536158, 3)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM50397646(CHEMBL2181804 | US8536158, A)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102441(US8536158, E)copy SMILEScopy InChI
Affinity DataKi:  258nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics Limited

US Patent
LigandPNGBDBM102439(US8536158, C)copy SMILEScopy InChI
Affinity DataKi:  979nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BH6US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Tested for binding activity against [3H]-LTB4 to whole human neutrophil with halh maximal inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q298862KPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q298862KPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 10.7nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062383(3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 15.3nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062383(3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 15.6nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062383(3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 17.9nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062379(3-Cyclopentyloxy-N-(1-hydroxycarbamoyl-ethyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 20.2nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062379(3-Cyclopentyloxy-N-(1-hydroxycarbamoyl-ethyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 22.2nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062383(3-Cyclopentyloxy-N-hydroxycarbamoylmethyl-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 27.2nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetLeukotriene B4 receptor 1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)copy SMILEScopy InChI
Affinity DataIC50: 30.3nMAssay Description:Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q298862KPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 31.6nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 35.7nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062379(3-Cyclopentyloxy-N-(1-hydroxycarbamoyl-ethyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 50.7nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062381(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-methyl-4,5...)copy SMILEScopy InChI
Affinity DataIC50: 95.2nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062379(3-Cyclopentyloxy-N-(1-hydroxycarbamoyl-ethyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair