Compile Data Set for Download or QSAR
Found 214 with Last Name = 'tan' and Initial = 'esw'
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257135(CHEMBL4080208)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257160(CHEMBL4096728)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257143(CHEMBL4080021)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455611(CHEMBL4212424)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455569(CHEMBL4202753)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50133866(CHEMBL3633802)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455593(CHEMBL4208685)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455592(CHEMBL4206065)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257141(CHEMBL4069295)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455602(CHEMBL4216507)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257139(CHEMBL4104447)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375523(4-(6-(4-(4-(dimethylamino)piperidine-1-carbonyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257144(CHEMBL4066589)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-zeta expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375523(4-(6-(4-(4-(dimethylamino)piperidine-1-carbonyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257145(CHEMBL4095609)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257142(CHEMBL4096529)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257138(CHEMBL4066796)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257136(CHEMBL4061069)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257137(CHEMBL4094309)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375525(4-(6-(4-(piperazine-1-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375513((4-(3-(4-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375522(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257134(CHEMBL4066798)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375513((4-(3-(4-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375525(4-(6-(4-(piperazine-1-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257158(CHEMBL4104257)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257161(CHEMBL4075204)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455566(CHEMBL4208028)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455538(CHEMBL4214092)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375522(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257162(CHEMBL4102043)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455611(CHEMBL4212424)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455611(CHEMBL4212424)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455538(CHEMBL4214092)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257129(CHEMBL4088085)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455593(CHEMBL4208685)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375544(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455594(CHEMBL4212934)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257159(CHEMBL4086549)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455569(CHEMBL4202753)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257140(CHEMBL4078705)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375543(4-(6-(4-(4-Methylpiperazine-1-carbonyl)phenyl)imid...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375543(4-(6-(4-(4-Methylpiperazine-1-carbonyl)phenyl)imid...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375544(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM50455610(CHEMBL4211722)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N5ZPubMed
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