Compile Data Set for Download or QSAR
Found 177 with Last Name = 'colotta' and Initial = 'f'
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31541(pyrazolo[4,3-h]quinazoline-3-carboxamide, 24)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50475205(CHEMBL190899)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31532(pyrazolo[4,3-h]quinazoline-3-carboxamide, 1)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329419(5-(2-amino-5-bromopyrimidin-4-yl)-2-p-tolyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31539(pyrazolo[4,3-h]quinazoline-3-carboxamide, 22)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329420(5-(2-amino-5-chloropyrimidin-4-yl)-2-p-tolyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329417(5-(3-Fluoro-pyridin-4-yl)-2-phenyl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329416(2-(2-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329418(2-Phenyl-5-pyridin-4-yl-1H-pyrrole-3-carboxamide |...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM27344(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31542(pyrazolo[4,3-h]quinazoline-3-carboxamide, 25)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329415(2-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31544(pyrazolo[4,3-h]quinazoline-3-carboxamide, 27)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329426(5-(2-Amino-5-fluoro-pyrimidin-4-yl)-2-phenyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31533(pyrazolo[4,3-h]quinazoline-3-carboxamide, 16)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329433(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-2-yl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329427(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329425(2-(3-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329414(2-(4-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31543(pyrazolo[4,3-h]quinazoline-3-carboxamide, 26)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31549(pyrazolo[4,3-h]quinazoline-3-carboxamide, 32)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31541(pyrazolo[4,3-h]quinazoline-3-carboxamide, 24)copy SMILEScopy InChI
Affinity DataIC50: 30nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31546(pyrazolo[4,3-h]quinazoline-3-carboxamide, 29)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31557(pyrazolo[4,3-h]quinazoline-3-carboxamide, 40)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31553(pyrazolo[4,3-h]quinazoline-3-carboxamide, 36)copy SMILEScopy InChI
Affinity DataIC50: 36nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329468(5-(2-Amino-pyrimidin-4-yl)-1-trifluoroethyl-2-phen...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329424(5-(2-aminopyrimidin-4-yl)-4-chloro-2-phenyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329471(2-(2-Nitro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329430(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-3-yl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329422(5-(2-Amino-pyrimidin-4-yl)-1-ethyl-2-phenyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329423(2-(3-Nitro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31540(pyrazolo[4,3-h]quinazoline-3-carboxamide, 23)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31550(pyrazolo[4,3-h]quinazoline-3-carboxamide, 33)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31532(pyrazolo[4,3-h]quinazoline-3-carboxamide, 1)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50088570((S)-2-(3-Benzoyl-phenyl)-propionic acid | (S)-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31542(pyrazolo[4,3-h]quinazoline-3-carboxamide, 25)copy SMILEScopy InChI
Affinity DataIC50: 51nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329472(5-(2-amino-pyrimidin-4-yl)-4-iodo-2-phenyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329463(2-Phenyl-5-(2-phenylamino-pyrimidin-4-yl)-1H-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)copy SMILEScopy InChI
Affinity DataIC50: 53nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31539(pyrazolo[4,3-h]quinazoline-3-carboxamide, 22)copy SMILEScopy InChI
Affinity DataIC50: 53nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31551(pyrazolo[4,3-h]quinazoline-3-carboxamide, 34)copy SMILEScopy InChI
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329470(2-(3-Bromo-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329465(2-(3-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31555(pyrazolo[4,3-h]quinazoline-3-carboxamide, 38)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl

LigandPNGBDBM31552(pyrazolo[4,3-h]quinazoline-3-carboxamide, 35)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3JJPPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329431(5-Pyridin-4-yl-2-p-tolyl-1H-pyrrole-3-carboxamide ...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329466(5-(2-Amino-pyrimidin-4-yl)-2-benzo[b]thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
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