Compile Data Set for Download or QSAR
Found 17 with Last Name = 'grzemski' and Initial = 'f'
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319612((R)-(+)-4-[4,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319613((R)-(+)-4-(1-(2-Fluorobenzyl)-4,4-dimethyl-2-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319613((R)-(+)-4-(1-(2-Fluorobenzyl)-4,4-dimethyl-2-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 174nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319612((R)-(+)-4-[4,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 488nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319613((R)-(+)-4-(1-(2-Fluorobenzyl)-4,4-dimethyl-2-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 4.82E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 6.95E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319612((R)-(+)-4-[4,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed