Compile Data Set for Download or QSAR
Found 12 with Last Name = 'habens' and Initial = 'f'
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19153((1S,7R,10S,16E,21R)-7,21-bis(propan-2-yl)-2-oxa-12...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19152((1S,7R,10S,16E,21R)-21-methyl-7-(propan-2-yl)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 3.97nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19154((6R,9R,12R,16R)-9,12-dimethyl-6-(propan-2-yl)-16-[...)copy SMILEScopy InChI
Affinity DataIC50: 17.5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19155((6R,9S,12R,16R)-16-[(1E)-4-(acetylsulfanyl)but-1-e...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 196nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Southampton

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 775nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 787nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19152((1S,7R,10S,16E,21R)-21-methyl-7-(propan-2-yl)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 881nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19153((1S,7R,10S,16E,21R)-7,21-bis(propan-2-yl)-2-oxa-12...)copy SMILEScopy InChI
Affinity DataIC50: 897nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19154((6R,9R,12R,16R)-9,12-dimethyl-6-(propan-2-yl)-16-[...)copy SMILEScopy InChI
Affinity DataIC50: 4.92E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed
TargetHistone deacetylase 6(Mus musculus)
University of Southampton

LigandPNGBDBM19155((6R,9S,12R,16R)-16-[(1E)-4-(acetylsulfanyl)but-1-e...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N4BPubMed