Compile Data Set for Download or QSAR
Found 162 with Last Name = 'klein' and Initial = 'f'
Target5-hydroxytryptamine receptor 2A(Bovine)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)copy SMILEScopy InChI
Affinity DataKi:  7.20nMAssay Description:Compound was evaluated for the binding affinity at 5- HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Compound was evaluated for the binding affinity at Alpha adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM50031474((2E)-2-[(5-hydroxy-1H-indol-3-yl)methylene]hydrazi...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Compound was evaluated for the binding affinity at 5- HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
TargetD(2) dopamine receptor(Bovine)
Sandoz Pharma Limited

Curated by ChEMBL
LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Compound was evaluated for the binding affinity at Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959VMPubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50403370(CHEMBL2052021 | CP-71362)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Compound was tested for its inhibitory activity against dog plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XVS
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human PRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081073(CHEMBL3421889)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081072(CHEMBL3421890)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081069(CHEMBL3421871)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081072(CHEMBL3421890)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081101(CHEMBL3421879)copy SMILEScopy InChI
Affinity DataIC50: 0.790nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081068(CHEMBL3421872)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081063(CHEMBL3421875)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276129((2S,4bR,8aR)-4b-Ethyl-7-phenyl-4b,5,6,7,8,8a,9,10-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081079(CHEMBL3421886)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081062(CHEMBL3421876)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081062(CHEMBL3421876)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276434((2R,4aR,10aR)-4a-Propyl-2-prop-1-ynyl-1,2,3,4,4a,9...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276127((2R,3S,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081101(CHEMBL3421879)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081071(CHEMBL3421891)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081079(CHEMBL3421886)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081095(CHEMBL3421885)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase type 4A (PDE4A).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276438((2R,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276126((2R,3S,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081075(CHEMBL3421887)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
LigandPNGBDBM50062387(3-(3-Cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1X11PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276437((2R,4aR,10aR)-4a-Ethyl-2-prop-1-ynyl-7-(pyridin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetRenin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50403370(CHEMBL2052021 | CP-71362)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Compound was tested for its inhibitory activity against Rat plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XVS
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276472((2R,3S,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081069(CHEMBL3421871)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276171((2R,4aS,10aR)-4a-Propenyl-2-prop-1-ynyl-1,2,3,4,4a...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276128((2R,3R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276128((2R,3R,4aR,10aR)-4a-Ethyl-2-phenyl-1,2,3,4,4a,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081073(CHEMBL3421889)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081075(CHEMBL3421887)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081067(CHEMBL3421873)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276170((2R,4aR,10aR)-4a-Ethyl-2-prop-1-ynyl-1,2,3,4,4a,9,...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081095(CHEMBL3421885)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276475((2R,4aR,10aR)-4a-Ethyl-7-(2-methylpyridin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23778M0PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081068(CHEMBL3421872)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM891CPubMed
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