Compile Data Set for Download or QSAR
Found 317 with Last Name = 'menzaghi' and Initial = 'f'
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
SIBIA Neurosciences Inc.

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC02PQPubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(RAT)
SIBIA Neurosciences Inc.

Curated by ChEMBL
LigandPNGBDBM50077117(4-[2-(1-Methyl-pyrrolidin-2-yl)-ethylsulfanyl]-phe...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC02PQPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc.

Curated by PDSP Ki Database
LigandPNGBDBM50052594((+) 3-Bromo-5-(1-methyl-pyrrolidin-2-yl)-pyridine ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7H97PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc.

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of HUman embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7H97PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc.

Curated by PDSP Ki Database
LigandPNGBDBM50052592(3-Ethyl-5-(1-methyl-pyrrolidin-2-yl)-pyridine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7H97PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc.

Curated by PDSP Ki Database
LigandPNGBDBM50052593(3-Ethynyl-5-((S)-1-methyl-azetidin-2-yl)-pyridine ...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7H97PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc.

Curated by PDSP Ki Database
LigandPNGBDBM86544(CAS_192231-16-6 | CHEMBL111580 | NSC_6442277 | SIB...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7H97PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc.

Curated by PDSP Ki Database
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+5nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7H97PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235787(US9359399, 1)copy SMILEScopy InChI
Affinity DataEC50:  0.0430nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235785(CVD-0019439 | US9359399, 2)copy SMILEScopy InChI
Affinity DataEC50:  0.0480nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235793(US9359399, 3)copy SMILEScopy InChI
Affinity DataEC50:  0.0520nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235783(US9359399, 4)copy SMILEScopy InChI
Affinity DataEC50:  0.0750nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235784(US9359399, 5)copy SMILEScopy InChI
Affinity DataEC50:  0.0340nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235794(US9359399, 6)copy SMILEScopy InChI
Affinity DataEC50:  0.0360nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235795(US9359399, 7)copy SMILEScopy InChI
Affinity DataEC50:  0.0120nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235796(US9359399, 8)copy SMILEScopy InChI
Affinity DataEC50:  0.0430nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235797(US9359399, 9)copy SMILEScopy InChI
Affinity DataEC50:  0.0780nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235798(US9359399, 10)copy SMILEScopy InChI
Affinity DataEC50:  0.826nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235799(US9359399, 11)copy SMILEScopy InChI
Affinity DataEC50:  0.0520nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235800(US9359399, 12)copy SMILEScopy InChI
Affinity DataEC50:  0.0550nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235786(US9359399, 13)copy SMILEScopy InChI
Affinity DataEC50:  0.0320nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235801(US9359399, 14)copy SMILEScopy InChI
Affinity DataEC50:  0.349nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235802(US9359399, 15)copy SMILEScopy InChI
Affinity DataEC50:  0.0280nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235803(US9359399, 16)copy SMILEScopy InChI
Affinity DataEC50:  0.0210nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235804(US9359399, 17)copy SMILEScopy InChI
Affinity DataEC50:  0.0390nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235805(US9359399, 18)copy SMILEScopy InChI
Affinity DataEC50:  1.02nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235806(US9359399, 19)copy SMILEScopy InChI
Affinity DataEC50:  2.15nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235808(US9359399, 20)copy SMILEScopy InChI
Affinity DataEC50:  0.491nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235807(US9359399, 21)copy SMILEScopy InChI
Affinity DataEC50:  0.732nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235809(US9359399, 22)copy SMILEScopy InChI
Affinity DataEC50:  0.0950nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235788(US9359399, 23)copy SMILEScopy InChI
Affinity DataEC50:  0.0910nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235810(US9359399, 24)copy SMILEScopy InChI
Affinity DataEC50:  0.0360nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235811(US9359399, 25)copy SMILEScopy InChI
Affinity DataEC50:  0.0314nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235812(US9359399, 26)copy SMILEScopy InChI
Affinity DataEC50:  0.0194nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235813(US9359399, 27)copy SMILEScopy InChI
Affinity DataEC50:  0.00560nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235789(US9359399, 28)copy SMILES
Affinity DataEC50:  0.0582nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235814(US9359399, 29)copy SMILEScopy InChI
Affinity DataEC50:  0.0464nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235790(US9359399, 30)copy SMILES
Affinity DataEC50:  0.129nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235815(US9359399, 31)copy SMILEScopy InChI
Affinity DataEC50:  0.0216nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235816(US9359399, 32)copy SMILEScopy InChI
Affinity DataEC50:  0.0485nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235791(US9359399, 33)copy SMILEScopy InChI
Affinity DataEC50:  0.0767nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235817(US9359399, 34)copy SMILEScopy InChI
Affinity DataEC50:  0.354nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235818(US9359399, 35)copy SMILEScopy InChI
Affinity DataEC50:  0.0359nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235792(US9359399, 36)copy SMILES
Affinity DataEC50:  0.0234nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235787(US9359399, 1)copy SMILEScopy InChI
Affinity DataEC50:  0.150nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235785(CVD-0019439 | US9359399, 2)copy SMILEScopy InChI
Affinity DataEC50:  0.160nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235793(US9359399, 3)copy SMILEScopy InChI
Affinity DataEC50:  0.160nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235783(US9359399, 4)copy SMILEScopy InChI
Affinity DataEC50:  0.150nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235784(US9359399, 5)copy SMILEScopy InChI
Affinity DataEC50:  0.170nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Cara Therapeutics, Inc.

US Patent
LigandPNGBDBM235794(US9359399, 6)copy SMILEScopy InChI
Affinity DataEC50:  0.130nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z2CUS Patent
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