Found 95 with Last Name = 'oehme' and Initial = 'f' 
Affinity DataIC50: 50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 700nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 760nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 860nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 890nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 900nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 910nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 930nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.12E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 2.20E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 2.30E+3nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
