Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2/Cyclin A assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/Cyclin A assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl
Curated by ChEMBL
Nerviano Medical Sciences srl
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of PLK1 assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of CDK2/Cyclin A assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Nerviano Medical Sciences srl
Curated by ChEMBL
Nerviano Medical Sciences srl
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Nerviano Medical Sciences srl
Curated by ChEMBL
Nerviano Medical Sciences srl
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Nerviano Medical Sciences srl
Curated by ChEMBL
Nerviano Medical Sciences srl
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Nerviano Medical Sciences srl
Curated by ChEMBL
Nerviano Medical Sciences srl
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl
Curated by ChEMBL
Nerviano Medical Sciences srl
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of PLK1 assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Aur-A assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMT: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair