Compile Data Set for Download or QSAR
Found 260 with Last Name = 'sullivan' and Initial = 'f'
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)copy SMILEScopy InChI
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of recombinant KRAS G12C mutant (unknown origin) assessed as rate of inactivation by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532351(CHEMBL4565958)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532351(CHEMBL4565958)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539762(CHEMBL4632935)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539761(CHEMBL4648852)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120086(US8697715, 1 | US9259470, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120086(US8697715, 1 | US9259470, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532362(CHEMBL4436718)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532362(CHEMBL4436718)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120086(US8697715, 1 | US9259470, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120086(US8697715, 1 | US9259470, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539765(CHEMBL4640636)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120095(US10525036, Example GDC-0994 | US10934304, Example...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120095(US10525036, Example GDC-0994 | US10934304, Example...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532351(CHEMBL4565958)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532351(CHEMBL4565958)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532350(CHEMBL4571067)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539760(CHEMBL4636611)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532361(CHEMBL4435650)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532361(CHEMBL4435650)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as reduction in ERK phosphorylation incubated for 24 hrs by in-cell western methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532362(CHEMBL4436718)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532362(CHEMBL4436718)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM206343(US9259470, 167)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM206343(US9259470, 167)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539759(CHEMBL4646899)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120095(US10525036, Example GDC-0994 | US10934304, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120095(US10525036, Example GDC-0994 | US10934304, Example...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532361(CHEMBL4435650)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532361(CHEMBL4435650)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539766(CHEMBL4645376)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532349(CHEMBL4474917)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532349(CHEMBL4474917)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539754(CHEMBL4648671)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM206343(US9259470, 167)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120112(US8697715, 167)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120112(US8697715, 167)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM206343(US9259470, 167)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539753(CHEMBL4648056)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetGTPase KRas(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164C5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532352(CHEMBL4452981)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532352(CHEMBL4452981)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532363(CHEMBL4459138)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM50532363(CHEMBL4459138)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array BioPharma Inc

Curated by ChEMBL
LigandPNGBDBM120114(US8697715, 173 | US9259470, 173)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D42PubMed
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