Compile Data Set for Download or QSAR
Found 5505 with Last Name = 'von delft' and Initial = 'f'
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataKi:  1.97E+3nMAssay Description:Competitive inhibition of human KDM2A expressed in Escherichia coli using 2-oxoglutarate by enzyme kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395076(CHEMBL2164243)copy SMILEScopy InChI
Affinity DataKi:  8.50E+4nMAssay Description:Mixed type inhibition of human KDM2A expressed in Escherichia coli assessed inhibition constant for compound-enzyme-substrate complex using methyl ly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N9SPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM496902(CVD-0018409 | PF-07321332 | US11351149, Example 13...)copy SMILEScopy InChI
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153099(CHEMBL3775814)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153161(CHEMBL3775545)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153101(CHEMBL3774665)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151919(CHEMBL3775121)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of KDM6B (unknown origin) using biotin-H3K27me3 (21 to 44 residues) as substrate preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153181(CHEMBL3774692)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153181(CHEMBL3774692)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153092(CHEMBL3775894)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153094(CHEMBL3775277)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153076(CHEMBL3775516)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153075(CHEMBL3774940)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153073(CHEMBL3775451)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153092(CHEMBL3775894)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153077(CHEMBL3775040)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM496478(LOR-NOR-30067bb9-11)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MS3WV7
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153069(CHEMBL3775953)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151917(CHEMBL3775548)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of KDM6B (unknown origin) using biotin-H3K27me3 (21 to 44 residues) as substrate preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153078(CHEMBL3774392)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM495599(CVD-0016335 | STE-KUL-d79e3d6a-3)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MS3WV7
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153073(CHEMBL3775451)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM495599(CVD-0016335 | STE-KUL-d79e3d6a-3)copy SMILEScopy InChI
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153077(CHEMBL3775040)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153076(CHEMBL3775516)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153075(CHEMBL3774940)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM6B (unknown origin) using biotin-H3K27me3 (21 to 44 residues) as substrate preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153099(CHEMBL3775814)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153072(CHEMBL3775956)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM496258(CVD-0013146 | JOH-MSK-46727e7b-1)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MS3WV7
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153074(CHEMBL3775465)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152119(CHEMBL3775362)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153070(CHEMBL3775977)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM496258(CVD-0013146 | JOH-MSK-46727e7b-1)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MS3WV7
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153101(CHEMBL3774665)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50153161(CHEMBL3775545)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50151919(CHEMBL3775121)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097TRPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM495290(CVD-0018692 | MAT-POS-e194df51-1)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
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