Compile Data Set for Download or QSAR
Found 40 with Last Name = 'serrano' and Initial = 'fg'
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007801(CHEMBL3233832)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-inhibitor complex by Li...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007801(CHEMBL3233832)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-substrate-inhibitor com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007795(CHEMBL3233826)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007796(CHEMBL3233827)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007801(CHEMBL3233832)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007797(CHEMBL3233828)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007799(CHEMBL3233830)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007798(CHEMBL3233829)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007802(CHEMBL3234038)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007803(CHEMBL3234039)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007804(CHEMBL3234040)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007801(CHEMBL3233832)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007800(CHEMBL3233831)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007799(CHEMBL3233830)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 222nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007800(CHEMBL3233831)copy SMILEScopy InChI
Affinity DataIC50: 265nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 321nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007798(CHEMBL3233829)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007804(CHEMBL3234040)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007801(CHEMBL3233832)copy SMILEScopy InChI
Affinity DataIC50: 513nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007799(CHEMBL3233830)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007803(CHEMBL3234039)copy SMILEScopy InChI
Affinity DataIC50: 645nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007795(CHEMBL3233826)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007798(CHEMBL3233829)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007796(CHEMBL3233827)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007802(CHEMBL3234038)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007802(CHEMBL3234038)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007803(CHEMBL3234039)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007797(CHEMBL3233828)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007804(CHEMBL3234040)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50007800(CHEMBL3233831)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50379274(CHEMBL2011499 | US9238626, (+)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50379273(CHEMBL1994202 | US9238626, (-)-Huprine Y HCl)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7BZ9PubMed