Compile Data Set for Download or QSAR
Found 107 with Last Name = 'clarke' and Initial = 'fh'
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042828(4-Hydroxy-1-(9-mercaptomethyl-10-oxo-azecane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016895(5-Methoxy-1-propyl-2,3,10,10a-tetrahydro-1H-9-oxa-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042835(1-(9-Mercaptomethyl-10-oxo-azecane-2-carbonyl)-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016900((E)-N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008790(5-[Pyridin-4-yl-(3-trifluoromethyl-phenyl)-methyle...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Compound was evaluated in vitro for the inhibition of Thromboxane synthase using [14C]-arachidonic acid as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042827(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042827(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptam...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016883(1-Propyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82427(CAS_5985-38-6 | LEVORPHANOL-tartarate)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82427(CAS_5985-38-6 | LEVORPHANOL-tartarate)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008798(7-(3-Pyridin-3-yl-bicyclo[2.2.1]hept-2-yl)-heptano...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016882(1-Butyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-p...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016888(1-Propyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016890(5-Methoxy-1-propyl-2,3,4,4a,10,10a-hexahydro-1H-9-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042832(3-Hydroxy-2-[(9-mercaptomethyl-10-oxo-azecane-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50228062(CHEMBL165290)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042831(6-Amino-2-[(9-mercaptomethyl-10-oxo-azecane-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016885(1-Propyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016899(8-Methoxy-1,5-dimethyl-2,3,4,4a,10,10a-hexahydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50497043(CHEMBL3249802)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50497043(CHEMBL3249802)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50228061(CHEMBL163167)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Compound was evaluated in vitro for the inhibition of Thromboxane synthase using [14C]-arachidonic acid as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008794(6-(3-Pyridin-3-yl-bicyclo[2.2.1]hept-2-yl)-hex-4-e...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016884(1-Propyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016882(1-Butyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-p...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016892(5-Methoxy-1,7-dimethyl-2,3,4,4a,10,10a-hexahydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008800(7-(3-Pyridin-3-yl-bicyclo[2.2.1]hept-2-yl)-hept-5-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [125I]- Iodocyanopindolol binding to 5-hydroxytryptamine 1B receptor at...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016894(1-Propyl-2,3,10,10a-tetrahydro-1H-9-oxa-1-aza-phen...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008797(7-(3-Pyridin-3-yl-bicyclo[2.2.1]hept-2-yl)-heptano...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008801(7-(3-Pyridin-3-yl-bicyclo[2.2.1]hept-2-yl)-hept-5-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042830(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042829(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016890(5-Methoxy-1-propyl-2,3,4,4a,10,10a-hexahydro-1H-9-...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016881(1-Propyl-2,3,10,10a-tetrahydro-1H-9-oxa-1-aza-phen...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016892(5-Methoxy-1,7-dimethyl-2,3,4,4a,10,10a-hexahydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016884(1-Propyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50008793(6-(3-Pyridin-3-yl-bicyclo[2.2.1]hept-2-yl)-hex-4-e...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8R47PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50042836(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X5DPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50016891(5-Methoxy-7-methyl-1-propyl-2,3,4,4a,10,10a-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin, binds to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NQ6PubMed
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