Affinity DataIC50: 0.800nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compound was evaluated in vitro for the inhibition of Thromboxane synthase using [14C]-arachidonic acid as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptam...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Compound was evaluated in vitro for the inhibition of Thromboxane synthase using [14C]-arachidonic acid as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [125I]- Iodocyanopindolol binding to 5-hydroxytryptamine 1B receptor at...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
CIBA-GEIGY Corporation
Curated by ChEMBL
CIBA-GEIGY Corporation
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin, binds to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair