Compile Data Set for Download or QSAR
Found 23 with Last Name = 'pavan' and Initial = 'fr'
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544190(CHEMBL4642912)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544189(CHEMBL4638488)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544187(CHEMBL4633659)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544193(CHEMBL1540399)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544183(CHEMBL4647549)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544188(CHEMBL4643280)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544184(CHEMBL4638799)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544195(CHEMBL4639355)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM38964(3-[(4-methoxyphenoxy)methyl]benzoic acid | MLS0000...)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544191(CHEMBL4635914)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544186(CHEMBL4638822)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544192(CHEMBL4644947)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544182(CHEMBL4649874)copy SMILEScopy InChI
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50508821(CHEMBL4443020)copy SMILEScopy InChI
Affinity DataIC50: 4.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544194(CHEMBL4634216)copy SMILEScopy InChI
Affinity DataIC50: 4.54E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544196(CHEMBL4637819)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544185(CHEMBL4638943)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen

Curated by ChEMBL
LigandPNGBDBM50544181(CHEMBL4649468)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4TH6PubMed