TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2B6(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 4.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 4.54E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£bingen
Curated by ChEMBL
University Hospital T£bingen
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
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