Compile Data Set for Download or QSAR
Found 84 with Last Name = 'deyanat-yazdi' and Initial = 'g'
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317482(4-(4-((1s,4s)-4-hydroxy-4- methylcyclohexyloxy)-5-...)copy SMILES
Affinity DataIC50: 1.15nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317480(4-(4-isopropoxy-5-(4- (methylcarbamoyl)phenyl)-7H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.42nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317482(4-(4-((1s,4s)-4-hydroxy-4- methylcyclohexyloxy)-5-...)copy SMILES
Affinity DataIC50: 1.43nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317475(3-cyano-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.47nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317466(4-(4-methoxy-5-(pyridin-4-yl)- 7H-pyrrolo[2,3-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317471((S)-3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazo...)copy SMILES
Affinity DataIC50: 1.68nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317467(3-methoxy-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.68nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317485(3-chloro-N-methyl-4-(5-(1- methyl-1H-pyrazol-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.91nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317483(3-chloro-N-methyl-4-(5-(4- (methylcarbamoyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317473(4-(5-(4-(1H-imidazol-2- yl)phenyl)-4-(tetrahydro-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.12nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317468(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 2.13nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317471((S)-3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazo...)copy SMILES
Affinity DataIC50: 2.27nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317469(3-methoxy-4-(4-methoxy-5-(6- methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.29nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317475(3-cyano-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.32nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317479(4-(4-cyclobutoxy-5-(4- (methylcarbamoyl)phenyl)-7H...)copy SMILEScopy InChI
Affinity DataIC50: 2.35nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.38nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317472(N,3-dimethyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 2.45nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317474(4-(4-cyclopropoxy-5-(2- methylbenzo[d]oxazol-6-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.96nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317485(3-chloro-N-methyl-4-(5-(1- methyl-1H-pyrazol-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.29nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317468(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.38nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317467(3-methoxy-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317476(N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4- (t...)copy SMILEScopy InChI
Affinity DataIC50: 3.65nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317470(3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-...)copy SMILEScopy InChI
Affinity DataIC50: 4.12nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317460(4-(5-(4-hydroxyphenyl)-4- (tetrahydro-2H-pyran-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 4.33nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317478(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 4.54nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317466(4-(4-methoxy-5-(pyridin-4-yl)- 7H-pyrrolo[2,3-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 4.56nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length recombinant GST-tagged TTK expressed in baculovirus by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317469(3-methoxy-4-(4-methoxy-5-(6- methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.14nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317481(4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.92nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged CLK2 expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317481(4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317477(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 8.06nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 8.17nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317476(N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4- (t...)copy SMILEScopy InChI
Affinity DataIC50: 9.41nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317477(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 10.4nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317484(3-chloro-4-(4-(cyclopentyloxy)-5- (2-methylbenzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 11.6nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317484(3-chloro-4-(4-(cyclopentyloxy)-5- (2-methylbenzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 12.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317463(4-(4-(cyclopentyloxy)-5-(6- methoxypyridin-3-yl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 13.3nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of CLK2 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317464(4-(4-(cyclopentyloxy)-5-(6- ethoxypyridin-3-yl)-7H...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317458(4-(4-(cyclopentylamino)-5-(4- hydroxyphenyl)-7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317470(3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-...)copy SMILEScopy InChI
Affinity DataIC50: 29.1nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317456(4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 34.9nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317472(N,3-dimethyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 40.1nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317466(4-(4-methoxy-5-(pyridin-4-yl)- 7H-pyrrolo[2,3-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 41.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317455(4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 53.9nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals, LLC

US Patent
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of TTK phosphorylation at T686 residue in human CAL51 cells after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
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